Chaotic Mixing of Powders and Slurries

粉末和浆料的混乱混合

基本信息

  • 批准号:
    9307773
  • 负责人:
  • 金额:
    $ 5万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    1993
  • 资助国家:
    美国
  • 起止时间:
    1993-03-01 至 1994-08-31
  • 项目状态:
    已结题

项目摘要

It is proposed to apply the chaos theory to mixing of particle systems, without and with an interstitial liquid, and to develop and experimental approach to quantify the mixture performance in a simple flow configuration. Mixing of particle systems is significant different from mixing of fluids due to the segregation and secondary phenomena caused by interparticle interactions. Even if mixing plays an important role in chemical, petroleum, mining and pharmaceutical processes, no reliable theory with a larger range of generality has been developed. The proposed approach offers a sound background for developing a chaos based theory, and a simple device for model calibration and testing. Several technological improvements are expected by the introduction of various disturbances which would enhance mixing of particulates. The research project to be focused on the differences between single fluid mixing and particulate mixing, and on the generic aspects which can be obtained from the experiments on the proposed device. The feasibility of the chaos theory applied to particulate mixing is a main goal of this project.
提出了将混沌理论应用于无间隙液体和有间隙液体的粒子系统的混合,并建立了一种实验方法来量化简单流动配置下的混合性能。由于粒子间相互作用引起的偏析和二次现象,粒子系统的混合与流体的混合有显著的不同。即使混合在化学、石油、采矿和制药过程中起着重要作用,也没有发展出具有更大范围普遍性的可靠理论。该方法为发展基于混沌的理论提供了良好的背景,并提供了一种简单的模型校准和测试装置。通过引入各种干扰来加强颗粒的混合,预计会有几项技术改进。该研究项目将侧重于单流体混合和颗粒混合的区别,以及从所提出的装置上的实验可以得到的一般方面。混沌理论应用于颗粒混合的可行性是本项目的主要目标。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Fernando Muzzio其他文献

Mixing Cell: a Device to Mimic Extent of Lubrication and Shear in Continuous Tubular Blenders
  • DOI:
    10.1208/s12249-019-1473-1
  • 发表时间:
    2019-07-23
  • 期刊:
  • 影响因子:
    4.000
  • 作者:
    Sara Moghtadernejad;M. Sebastian Escotet-Espinoza;Zhanjie Liu;Elisabeth Schäfer;Fernando Muzzio
  • 通讯作者:
    Fernando Muzzio
Assessment of Blend and Content Uniformity. Technical Discussion of Sampling Plans and Application of ASTM E2709/E2810
  • DOI:
    10.1007/s12247-014-9208-z
  • 发表时间:
    2014-12-25
  • 期刊:
  • 影响因子:
    2.700
  • 作者:
    James Bergum;Thomas Parks;James Prescott;Ravindra Tejwani;Jon Clark;William Brown;Fernando Muzzio;Samir Patel;Charles Hoiberg
  • 通讯作者:
    Charles Hoiberg
Multi-layer Raman chemical mapping to investigate the effect of API particle size and blending shear rate on API domain sizes in pharmaceutical tablets
  • DOI:
    10.1016/j.ijpharm.2022.122052
  • 发表时间:
    2022-08-25
  • 期刊:
  • 影响因子:
  • 作者:
    Shashwat Gupta;Benoît Igne;Thamer Omar;Andrés D. Román-Ospino;Douglas Hausner;Fernando Muzzio
  • 通讯作者:
    Fernando Muzzio
Comparison of granules obtained with two twin-screw granulators of different diameter working at the same shear rate
对在相同剪切速率下工作的两台不同直径的双螺杆制粒机所获得的颗粒进行比较
  • DOI:
    10.1016/j.powtec.2025.121092
  • 发表时间:
    2025-08-01
  • 期刊:
  • 影响因子:
    4.600
  • 作者:
    Nazareth E. Ceschan;María C. Balbi;Pablo Ravazzoli;German Drazer;Fernando Muzzio;Gerardo Callegari
  • 通讯作者:
    Gerardo Callegari
Quantitative validation and analysis of the regime map approach for the wet granulation of industrially relevant zirconium hydroxide powders
  • DOI:
    10.1016/j.powtec.2016.02.026
  • 发表时间:
    2016-06-01
  • 期刊:
  • 影响因子:
  • 作者:
    Manogna Adepu;Siddhi Hate;Angelique Bétard;Sarang Oka;Marek Schongut;Maitraye Sen;Yadvaindera Sood;Dorit Wolf;Stefan Wieland;Frantisek Stepanek;Fernando Muzzio;Benjamin Glasser;Rohit Ramachandran
  • 通讯作者:
    Rohit Ramachandran

Fernando Muzzio的其他文献

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{{ truncateString('Fernando Muzzio', 18)}}的其他基金

Engineering Research Center (ERC) for Structured Organic Composites for Pharmaceutical, Nutraceutical, and Agrochemical Applications(C-SOC)
医药、保健品和农用化学品应用结构化有机复合材料工程研究中心 (ERC) (C-SOC)
  • 批准号:
    0540855
  • 财政年份:
    2006
  • 资助金额:
    $ 5万
  • 项目类别:
    Cooperative Agreement
IGERT: NanoPharmaceutical Engineering and Science
IGERT:纳米制药工程与科学
  • 批准号:
    0504497
  • 财政年份:
    2005
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing Grant
I/UCRC Proposal from Rutgers University to Join the Purdue/UConn/Minnesota/Puerto Rico Center for Pharmaceutical Processing
I/UCRC 罗格斯大学关于加入普渡大学/康涅狄格大学/明尼苏达州/波多黎各药物加工中心的提案
  • 批准号:
    0342240
  • 财政年份:
    2003
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
Renovation of Unusable Laboratories into a Modern Pharmaceutical Engineering Research Facility
将废弃实验室改造成现代制药工程研究设施
  • 批准号:
    9602602
  • 财政年份:
    1996
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
Using Mixing to Minimize Waste in Reactive Systems
利用混合最大限度地减少反应系统中的浪费
  • 批准号:
    9414460
  • 财政年份:
    1994
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing Grant

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