Interactions Between Monolayers and Molecules: A Basis for Molecular Recognition

这项资助是对克鲁克斯教授在有组织化学系统中观察到的分子识别现象的基础研究的更新。分析和表面化学计划的项目将涉及有机硫化合物在金表面化学吸附的薄膜，即所谓的自组装单层（SAMs）的实验和理论研究。研究将集中在探针分子与吸附单层之间的静电和氢键相互作用上。本研究的目标是开发可用于化学传感器的分子识别策略。克鲁克斯教授和他的同事将研究吸附在金表面的自组装有机硫化合物单层的化学性质。研究成果将用于开发基于分子识别现象的新型化学传感器、新型电子材料和创新光刻技术。

This grant is a renewal of Professor Crooks' fundamental investigation of molecular recognition phenomena observed in organized chemical systems. The project in the Analytical and Surface Chemistry Program will involve experimental and theoretical studies of thin films of organosulfur compounds chemisorbed on gold surfaces, i. e., so-called self-assembled monolayers (SAMs). The investigations will center on the electrostatic and hydrogen-bonding interactions between probe molecules and the adsorbed monolayers. The goal of the research is to develop molecular recognition strategies which can be used for chemical sensors. %%% Professor Crooks and his colleagues will investigate the chemistry of self-assembled monolayers of organosulfur compounds adsorbed on gold surfaces. The research results will be used for the development of new chemical sensors based on molecular recognition phenomena, new electronic materials and innovative lithographic techniques.