Chemical Sensors Based on Novel, Ultrathin Organic Coatings

该项目由德克萨斯农工大学的理查德·克鲁克斯教授执行，由分析和表面化学计划资助，涉及新有机材料的设计、合成、表征和表面固定，这些材料旨在用作基于阵列的传感器中的化学敏感器件。这项提议关注的有机材料是超支化聚合物膜和树枝状聚合物。基于树枝状单分子膜的气相化学传感器采用表面声波质量天平进行表征。固定化薄膜的化学灵敏度与树枝状结构的物理性质和预期设计相关，并将进行迭代以实现所需的化学选择性。这些薄膜在阵列中用于挥发性有机化合物的测定将在合作努力中进行探索。探索了一种组合化学方法来制备新的用于传感的有机化合物，并寻求了一种新的双层膜固定化方法，以保持选择性并保护表面免受毒害。化学传感器的用途取决于传感器表面材料的特性。德克萨斯农工大学的理查德·克鲁克斯教授的这项工作开发了一种新的高度分支的材料，具有可预测的特性和更好的响应。一种将材料连接到传感器表面的方法也在开发中，该方法可以保护传感膜不受损害和中毒。

This project, carried out by Professor Richard Crooks at Texas A&M University, and funded by the Analytical and Surface Chemistry Program, involves the design, synthesis, characterization, and surface immobilization of new organic materials intended to serve as chemically sensitive devices in array-based sensors. The organic materials that are the focus of this proposal are hyberbranched polymer films and dendritic polymers. Vapor phase chemical sensors based on dendritic monolayers are characterized by surface acoustic wave mass balances. The chemical sensitivities of the immobilized films are correlated with the physical properties and intended design of the dendritic structure, and an iteration to achieve the desired chemical selectivity will be pursued. Use of these thin films in arrays for volatile organic compound determinations will be explored in collaborative efforts. A combinatorial chemistry approach to the preparation of new organic compounds to be used for sensing is explored, and a novel means for bilayer film immobilization that preserves selectivity and protects the surface from poisoning is also pursued.The usefulness of chemical sensors depends on the specificity of the material on the surface of the sensor. This work by Professor Richard Crooks of Texas A&M University develops new highly branched materials with predictable specificities and better responses. A means to connect the material to the sensor surface that protects the sensing film from damage and poisoning is also being developed.