Cyanophages of Marine Synechococcus: A Model System to Evaluate the Impact of Viruses on the Population Structure and Dynamics of Planktonic Bacteria

海洋聚球藻的噬藻体：评估病毒对浮游细菌种群结构和动态影响的模型系统

• 批准号: 9315895
• 负责人: John Waterbury
• 金额: $ 35.86万
• 依托单位: Woods Hole Oceanographic Institution
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-02-15 至 1999-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9315895&HistoricalAwards=false
• 关键词: Cyanophages; Marine; Synechococcus; Model; System

Waterbury 9315895 Previous studies by this investigator have confirmed that the presence of a diverse group of marine cyanobacterial phages that are capable of infecting Synechococcus and that they can occur at extremely high titers of 104 phage particles per milliliter. In addition, Waterbury has shown that a natural bacterial population and its phages follow the patterns predicted from modeling and chemostat studies of E. coli and its virulent phages. Thus, Waterbury hypothesizes that due to the acquisition of resistance, virulent Synechococcus phages play an important role in determining the clonal composition of natural Synechococcus populations, but that they have little effect on the overall population densities or mortality. To test this hypothesis, a laboratory project is designed to develop ribonucleic acid and antibody probes to follow the species dynamics of Synechococcus and its phages, respectively. This host-parasite system will prove to be an excellent model to examine the role of bacteriophages in the oceans. ***

沃特伯里9315895 该研究人员以前的研究已经证实，存在一组能够感染聚球藻的海洋蓝藻，并且它们可以以每毫升104个噬菌体颗粒的极高滴度发生。 此外，沃特伯里还表明，天然细菌种群及其繁殖遵循的模式预测模型和恒化器研究的大肠杆菌。大肠杆菌及其毒力菌株 因此，沃特伯里假设，由于获得抗性， 聚球藻是一种重要的 作用 在确定天然聚球藻种群的克隆组成，但它们对总的人口密度或死亡率的影响不大。 为了验证这一假设，设计了一个实验室项目来开发核糖核酸和抗体探针，以分别跟踪聚球藻及其亚种的物种动态。这个宿主-寄生虫系统将证明 成为一个优秀的榜样， 海洋中的噬菌体。 ***