Collection of Mutant Types of Drosophila Melanogaster

黑腹果蝇突变类型的收集

• 批准号: 9403760
• 负责人: Kathleen Matthews
• 金额: $ 177.53万
• 依托单位: Indiana University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-15 至 1999-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9403760&HistoricalAwards=false
• 关键词: Collection; Mutant; Types; Drosophila; Melanogaster

Abstract BIR9403760 The Bloomington Drosophila Stock Center collects, maintains, and distributes genetic stocks of the fly, Drosophila melanogaster. The sophisticated genetic tools developed in Drosophila over the past 80 years make this insect a powerful model organisms for biological research. The collection currently consists of over 5,300 different genetic stocks including visible, lethal and sterile mutations (about 30% of the collection), chromosome aberrations (about 36% of the total), and marked transposon insertions (about 34% of holdings). An electronic database is maintained and distributed, allowing users full access to up-to- date information about stocks available from the collection, and center scientists are available to provide advice on the use of these materials. The center is heavily used, with close to 16,000 stocks expected to be shipped during 1993. Over 99% of stocks are used by academia-based researchers, about 76% of these within the US and the remaining 24% spread among 33 countries. This resource preserves valuable research materials for the future, promotes effective use of these tools today, assures that documented strains are readily available to all qualified users, and relieves individual researchers and their grants of the burden of providing large numbers of stocks to colleagues. This award is jointly supported with the National Center for Research Resouces, the National Institute of General Medical Sciences, and the National Eye Institute of the National Institutes of Health.

摘要 BIR9403760 布卢明顿果蝇库存中心收集、维护和分发果蝇的遗传库存。 过去 80 年来在果蝇中开发的复杂遗传工具使这种昆虫成为生物学研究的强大模式生物。 该收藏目前由 5,300 多个不同的遗传库组成，包括可见的、致命的和不育突变（约占收藏的 30%）、染色体畸变（约占总数的 36%）和标记的转座子插入（约占收藏的 34%）。 维护和分发电子数据库，使用户能够全面访问有关馆藏中可用库存的最新信息，并且中心科学家可以就这些材料的使用提供建议。 该中心的使用量很大，预计 1993 年将运送近 16,000 个库存。超过 99% 的库存供学术界研究人员使用，其中约 76% 在美国，其余 24% 分布在 33 个国家/地区。 该资源为未来保留了宝贵的研究材料，促进了当今这些工具的有效使用，确保所有合格的用户都可以轻松获得记录的菌株，并减轻了个人研究人员及其资助者向同事提供大量库存的负担。 该奖项由国家研究资源中心、国家普通医学科学研究所和美国国立卫生研究院国家眼科研究所联合支持。