Collection of Mutant Types of Drosophila Melanogaster

摘要 BIR9403760 布卢明顿果蝇库存中心收集、维护和分发果蝇（Drosophila melanogaster）的遗传库存。 在过去的80年里，在果蝇中开发的复杂的遗传工具使这种昆虫成为生物学研究的强大模式生物。 目前，该系列包括超过5，300种不同的遗传库存，包括可见的，致命的和不育的突变（约占总数的30%），染色体畸变（约占总数的36%）和标记的转座子插入（约占总数的34%）。 维持和分发一个电子数据库，使用户能够充分获得关于收藏品中现有股票的最新信息，中心的科学家可以就使用这些材料提供咨询意见。 该中心的使用率很高，预计1993年将运送近16 000批存货。 超过99%的股票是由总部位于迈阿密的研究人员使用的，其中约76%在美国，其余24%分布在33个国家。 这一资源为未来保存了宝贵的研究材料，促进了今天对这些工具的有效使用，确保所有合格的用户都可以随时获得记录在案的菌株，并减轻了研究人员及其资助者向同事提供大量库存的负担。 该奖项由国家研究资源中心、国家普通医学科学研究所和国立卫生研究院国家眼科研究所共同支持。

Abstract BIR9403760 The Bloomington Drosophila Stock Center collects, maintains, and distributes genetic stocks of the fly, Drosophila melanogaster. The sophisticated genetic tools developed in Drosophila over the past 80 years make this insect a powerful model organisms for biological research. The collection currently consists of over 5,300 different genetic stocks including visible, lethal and sterile mutations (about 30% of the collection), chromosome aberrations (about 36% of the total), and marked transposon insertions (about 34% of holdings). An electronic database is maintained and distributed, allowing users full access to up-to- date information about stocks available from the collection, and center scientists are available to provide advice on the use of these materials. The center is heavily used, with close to 16,000 stocks expected to be shipped during 1993. Over 99% of stocks are used by academia-based researchers, about 76% of these within the US and the remaining 24% spread among 33 countries. This resource preserves valuable research materials for the future, promotes effective use of these tools today, assures that documented strains are readily available to all qualified users, and relieves individual researchers and their grants of the burden of providing large numbers of stocks to colleagues. This award is jointly supported with the National Center for Research Resouces, the National Institute of General Medical Sciences, and the National Eye Institute of the National Institutes of Health.