LSC: Bloomington Drosophila Stock Center at Indiana University

LSC：印第安纳大学布卢明顿果蝇库存中心

• 批准号: 0841154
• 负责人: Kathleen Matthews
• 金额: $ 330.25万
• 依托单位: Indiana University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2014-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0841154&HistoricalAwards=false
• 关键词: LSC; Bloomington; Drosophila; Stock; Center

Abstract This is a five-year renewal award to the Bloomington Drosophila Stock Center (BDSC) at Indiana University. Dr. Kathleen Matthews in the Department of Biology is the PI and CoPIs include Drs. Kevin Cook and Thomas Kaufman. The BDSC is an internationally-recognized stock center that collects, maintains and distributes genetic stocks of the fly Drosophila melanogaster. It supports a large and active research community investigating fundamental biological processes through the use of the sophisticated genetic tools developed in this popular model organism. Its current user base includes more than 2,400 research groups and 35 teaching units in 56 countries. 61% of Center use comes from U.S. scientists and 98% of use comes from academic researchers. BDSC provides a comprehensive selection of strains supporting the full spectrum of Drosophila research. The collection consists of over 20,000 different genetic strains containing over 95,000 defined genetic elements including mutations, chromosomal aberrations and transposon insertions as well as tools for gene misexpression, site-specific recombination and transgenesis. BDSC will continue to maintain a website which will provide information concerning stocks, their experimental uses, ordering and account information, and regulatory issues. Information about genetic components of Bloomington stocks is fully integrated into FlyBase, the primary genetic and genomics database for Drosophila workers. Drosophila strains from Bloomington have been key components in experiments in gene regulation, cell biology, developmental biology, neurobiology, behavioral biology, population biology, ecology and evolution and will continue to have a broad impact in many fields of biological endeavor. The Center will assure that the stocks are used effectively by making BDSC information available through databases and websites found at http://flystocks.bio.indiana.edu

这是印第安纳大学布卢明顿果蝇种群中心（BDSC）获得的一项为期五年的更新奖。生物系的凯瑟琳·马修斯博士是首席研究员，首席研究员包括。凯文·库克和托马斯·考夫曼。BDSC是一个国际公认的收集、维护和分发果蝇遗传库存的库存中心。它支持一个庞大而活跃的研究团体，通过使用在这种流行的模式生物中开发的复杂遗传工具来调查基本的生物过程。它目前的用户群包括56个国家的2400多个研究小组和35个教学单位。61%的Center用户来自美国科学家，98%的用户来自学术研究人员。BDSC提供了一个全面的菌株选择，支持果蝇研究的全谱。该集合包括超过20,000种不同的遗传菌株，包含超过95,000种定义的遗传元件，包括突变，染色体畸变和转座子插入，以及基因错误表达，特定位点重组和转基因的工具。BDSC将继续维护一个网站，提供有关库存、试验用途、订购和账户信息以及监管问题的信息。有关布卢明顿种群遗传成分的信息已完全整合到果蝇工蜂的主要遗传和基因组数据库FlyBase中。来自Bloomington的果蝇菌株已经成为基因调控、细胞生物学、发育生物学、神经生物学、行为生物学、种群生物学、生态学和进化等实验的关键组成部分，并将继续在生物学的许多领域产生广泛的影响。中心将通过http://flystocks.bio.indiana.edu上的数据库和网站提供BDSC信息，确保这些库存得到有效利用