Synthetic Studies in the Field of Natural Product Chemistry

天然产物化学领域的合成研究

• 批准号: 9408247
• 负责人: Yoshito Kishi
• 金额: $ 86.23万
• 依托单位: Harvard University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-06-01 至 1997-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9408247&HistoricalAwards=false
• 关键词: Synthetic; Studies; Field; Natural; Product

9408247 Kishi The focus of this research will involve seven parts. The total synthesis and investigation of conformational changes of palytoxin, the conformational analysis of C- and O-glycosides, the conformational analysis of fatty acids and their derivatives, the structure elucidation and synthesis of AAL toxins and Fumonisins, the study of Ni(II)/Cr(II) mediated coupling reactions, the development of tripodal ligand chemistry and studies involving bioluminescence chemistry will all be carried out. %%% With this renewal award, the Synthetic Organic Program supports the research of Dr. Yoshito Kishi of the Department of Chemistry at Harvard University. Professor Kishi will focus his work on synthetic and conformational studies of complex biomolecules. ***

9408247 Kishi本研究的重点将涉及七个部分。 海葵毒素的全合成及构象变化研究，C-和O-糖苷的构象分析，脂肪酸及其衍生物的构象分析，AAL毒素和伏马菌素的结构鉴定和合成，Ni（II）/Cr（II）介导偶联反应的研究，三脚架配体化学的开发和涉及生物发光化学的研究都将进行。 %有了这个更新的奖项，合成有机计划支持哈佛大学化学系的Yoshito Kishi博士的研究。 Kishi教授将专注于复杂生物分子的合成和构象研究。 ***