Synthesis and Characterization of Dicyanoanthracene- Substituted-Beta-Cyclodextrins

9412515威廉和玛丽学院的超分子宿主将被合成，其中9，10-二氰基并与β-环糊精连接、封端和夹杂。将用荧光分光光度法研究东道主和猝灭客人之间的相互作用。将开发几种分析方法来阐明静态和动态淬火成分。最终目标是确定导致强结合和大静态/动态猝灭比的结构基序。这样的载体将是理想的光致电子转移催化剂。来自有机动力学项目的这笔赠款支持威廉与玛丽学院克里斯托弗·J·阿贝尔特教授的继续工作。悬挂式有机分子可以在紫外光照射下接受电子，它将与圆锥形的碳水化合物分子结合。碳水化合物分子可以作为其他分子(客体)的宿主，这些分子(客体)可以容纳在这个圆锥形的主体中。客体分子将是电子供体，因此在照射时，一个电子将从客体转移到悬挂的有机分子上。由于主体的体积限制了客体分子的场，因此会发生选择性的电子转移。

9412515 Abelt College of William and Mary Supramolecular hosts in which 9,10-dicyanoanthracene is tethered, capped, and sandwiched with beta-cyclodextrin will be synthesized. The interaction between the hosts and quenching guests will be studied by spectrofluorimetry. Several analytical methods will be developed to elucidate the static and dynamic quenching components. The ultimate goal is to identify the structural motifs that lead to both strong binding and a large static/dynamic quenching ratio. Such hosts will be ideal as photoinduced-electron-transfer catalysts. This grant from the Organic Dynamics Program supports the continuing work of Professor Christopher J. Abelt at the College of William and Mary. A pendant organic molecule, which can accept electrons upon ultraviolet light irradiation, will be bonded to a conically-shaped carbohydrate molecule. The carbohydrate molecule can act as a host to other molecules (guests) that can fit into this conically-shaped host. The guest molecules will be electron donors so that upon irradiation, an electron will be transferred from the guest to the pendant organic molecule. Since the volume of the host limits the field of guest molecules, selective electron transfer will occur.