U.S.-France Cooperative Research: Modeling 40 Hz Cortical Oscillations

美法合作研究：40 Hz 皮质振荡建模

• 批准号: 9416967
• 负责人: Xiao-Jing Wang
• 金额: --
• 依托单位: University of Pittsburgh
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-05-01 至 1997-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9416967&HistoricalAwards=false
• 关键词: U.S.; France; Cooperative; Research; Modeling

This three-year award will support U.S.-France cooperative research in biophysical modeling between Xiao-Jing Wang of the University of Pittsburgh and David Hansel of the Ecole Polytechnique, Paliseau, France. The objective of their research is to undertake biophysical modeling of 40 Hz oscillations in neurons and neural systems. They will address: rhythmogenesis; network mechanisms underlying synchronization and large variability; and the intermittent nature of 40 Hz oscillations. Rhythmic activity in mammalian brains at the 30 to 50 Hz oscillation rate has been shown to coincide with increased focal attention and may have important functional roles in perception and information processing. The proposed collaboration focuses on these physiological and cognitive issues by combining unique abilities of the investigators. The U.S. investigator brings to this collaboration expertise in biophysical modeling. This is complemented by the French investigator's expertise in the dynamics of large neural networks. Their joint effort will advance our knowledge of the physiological and biophysical mechanisms underlying neuronal cooperative rhythmically and its role in the organization of mammalian brain activity.

这个为期三年的奖项将支持美国-法国匹兹堡大学的王晓静和法国帕利索理工学院的大卫汉塞尔在生物物理建模方面的合作研究。 他们的研究目标是对神经元和神经系统中的40 Hz振荡进行生物物理建模。 它们将处理：节律发生;同步和大可变性的网络机制;以及40 Hz振荡的间歇性。 哺乳动物大脑在30至50 Hz振荡频率下的节律活动已被证明与焦点注意力的增加相一致，并且可能在感知和信息处理中具有重要的功能作用。 拟议的合作重点是通过结合研究人员的独特能力来解决这些生理和认知问题。美国研究人员为这项合作带来了生物物理建模方面的专业知识。这位法国研究人员在大型神经网络动态方面的专业知识对此进行了补充。 他们的共同努力将推进我们的知识的生理和生物物理机制的神经元合作的节奏和它的作用，在组织哺乳动物的大脑活动。