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Modulation of cardiac cell signaling with synthetic antibodies, and their characterization as potential therapeutics and probes for basic biological research

Modulation of cardiac cell signaling with synthetic antibodies, and their characterization as potential therapeutics and probes for basic biological research
用合成抗体调节心脏细胞信号传导,及其作为基础生物学研究潜在疗法和探针的表征
批准号:
366643
负责人:
Gramolini Anthony O
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-11-01 至 2017-11-01

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中文摘要
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英文摘要
The critical perturbations in molecular signaling that result in functional impairment of cardiac muscle cells are poorly understood. Our motivation is to understand the changes in the molecular mechanisms of cardiomyocytes in heart failure (HF) through t
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The role of reticulon homology domain (RHD) protein and related family members in the sarco(endo)plasmic formation and regulation in the cardiac myocyte
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Molecular Analyses of the Intercalated Disc Protein Tmem65 as a Novel Regulator of Cardiac Communication
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Detailed characterisation of the role of Reep5 in endo(sarco)plasmic formation, maintenance, and function in cardiac muscle
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Molecular basis of ryanodine receptor regulation and function in skeletal and cardiac muscle
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    259183
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海外基金