Dissertation Research: Developmental Analysis of Morphological Evolution: Convergence, Divergence, and the Origin of Novelties in Salamander Pigment Patterns

论文研究：形态进化的发展分析：蝾螈色素模式的趋同、趋异和新颖性的起源

• 批准号: 9423116
• 负责人: H. Bradley Shaffer
• 金额: $ 1.4万
• 依托单位: University of California-Davis
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-03-01 至 1997-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9423116&HistoricalAwards=false
• 关键词: Dissertation; Research; Developmental; Analysis; Morphological

9423116 Schaffer Vertebrate pigment cells are derived from the neural crest, a set of cells that also gives rise to the craniofacial skeleton, endocrine glands, the heart and the peripheral nervous system. This research will reveal some of the mechanisms that lead to this developmental diversification. Movements of pigment cells can be followed during development in amphibian eggs. The research will use molecular techniques and experimental manipulation to examine the interactions of neural crest cells with each other, with the extracellular matrix through which they migrate and with the lateral-line sensory system. The results will provide new insight into the mechanisms underlying pigment cell patterns, and ultimately, a deeper understanding of how developmental patterns have evolved to produce the diversity of structure we see within and between species.

脊椎动物的色素细胞来源于神经嵴，这组细胞也产生颅面骨骼、内分泌腺、心脏和周围神经系统。这项研究将揭示导致这种发育多样化的一些机制。在两栖动物卵的发育过程中，色素细胞的运动可以被跟踪。该研究将使用分子技术和实验操作来检查神经嵴细胞彼此之间的相互作用，与它们迁移的细胞外基质以及与侧线感觉系统的相互作用。这些结果将为色素细胞模式背后的机制提供新的见解，并最终更深入地了解发育模式是如何进化的，从而产生我们在物种内部和物种之间看到的结构多样性。