Career Direction through Integrated Introductory Biology- Chemistry Laboratory and Research

这项建议是一个三步连续的本科生生物化学体验，以留住理科专业的学生，并激励他们进入研究生涯。第一步是在学生的第一年，整合两个专业的生物和化学入门课程的第二学期实验室。讲座仍然是分开进行的。为了跟踪学生在综合实验室的经验，并保持和发展学生对科学研究的兴趣，第二步是大二春季的一门职业研讨必修课。来自学术界、医学界和产业界的研讨会演讲者担任参加第三步的学生的东道主，第三步是大学二年级和三年级之间的暑期研究实习。第二步和第三步在二年级同时进行，以提供综合第一年实验室的实际应用，并加强研究职业目标。两个实验室同时参与第一步，以追求一些非传统的、研究性的实验室模块，这些模块整合了细胞生物学、分子遗传学和普通化学的概念。每周7小时分为正式的实验室调查、讨论和复出时间。在12周的时间里，提出了四个单元。这些综合的模块化实验室将研究(1)维生素C代谢，(2)酶的反应动力学，(3)生命的能量来源，以及(4)大分子的操作。在每个模块的最后一周，学生分析数据，得出结论，并在选定的模块中，根据先前的实验设计他们自己的原始调查。有数学教程可供选择。这种综合的生物-化学模块模式直接与理科专业的现代研究型高年级课程相关，并为其做好准备，并与现实的职业研究经历平行。综合生物-化学实验室的一部分完全由女性组成，以便与其他两个混合性别的实验室进行比较，并与其他学生的传统的单独的生物和化学实验室进行比较。

This proposal is a three step sequential undergraduate biology-chemistry experience to retain science majors and to inspire them to enter research careers. Step I occurs in a student's first year with an integration of the second semester laboratories of the majors' Introductory Biology and Chemistry courses. Lectures remain separate. In order to follow the student experience of the integrated laboratories and to retain and build upon student interest in science research, Step II is a required Career Seminar course in Spring of the sophomore year. Seminar speakers from academia, medicine, and industry serve as hosts for students participating in Step III, a Summer Research internship between the second and third years of college. Steps II and III function together in the sophomore year to provide a practical application of the integrated first year laboratories and to reinforce research career goals. Two laboratory sections concurrently participate in Step I to pursue a number of nontraditional, investigative laboratory modules which integrate concepts from cell biology, molecular genetics, and general chemistry. Seven hours per week is divided into formal laboratory investigation, discussion, and comeback time. Over a 12-week period four modules are presented. These integrated, modular laboratories will examine (1) Vitamin C Metabolism, (2) Reaction Dynamics of Enzymes, (3) Sources of Energy for Life, and (4) Manipulation of Macromolecule. During the final week of each module, students analyze data, draw conclusions and in selected modules, design their own original investigations based on previous experimentation. Mathematic tutorials are available. This integrated, biological-chemical modular format directly relates to and prepares science majors for modern research-oriented upper division courses and parallel a realistic career research experience. One section of the integrated biology-chemistry laboratories is comprised entirely of women for comparison with the other two of mixed gender and with the traditional separate biology and chemistry laboratories for the other students.