NSF-CGP Science Engineering Fellows Program: Functional Role of Different Classes of Neocortical Inhibitory Interneurons in the Thalamocortical Circuit

9503844 Agmon本提案支持加州大学尔湾分校解剖学和神经生物系的Ariel Agmon博士和物理化学研究所（RIKEN）仿生控制研究中心的Yasuo Kawaguchi博士的合作。项目资金将使Agmon博士在日本的RIKEN呆一年，以研究丘脑皮层回路中不同类别的新皮层抑制性中间神经元的功能作用。Agmon博士之前研究过成熟和发育中的动物丘脑皮质连接的功能和形态组织。Kawaguchi博士在揭示皮层中抑制性中间神经元的形态和电生理特性的丰富多样性方面发挥了重要作用。Agmon博士将结合他与Kawaguchi博士的专业知识，研究丘脑皮质回路抑制的功能和形态组织。这项提议汇集了来自两个国家在神经解剖学和生理学领域工作的研究科学家。美国科学家将有机会熟悉RIKEN的研究技术、设备和设施，同时为整个研究工作做出贡献。因此，该提案通过国际合作实现了该计划在科学知识交流和转移方面的目标。＊＊＊

9503844 Agmon This proposal supports the collaboration of Dr. Ariel Agmon of the Department of Anatomy and Neurobiology at the University of California-Irvine and Dr. Yasuo Kawaguchi of the Bio-Mimetic Control Research Center of the Institute of Physical and Chemical Research (RIKEN). Project funding will enable Dr. Agmon to spend one year in Japan, resident at RIKEN, in order to study the functional role of different classes of neocortical inhibitory interneurons in the thalamocortical circuit. Dr. Agmon has previously studied the functional and morphological organization of thalamocortical connections in mature and developing animals. Dr. Kawaguchi has been instrumental in shedding light on the rich diversity of morphological and electrophysiological properties of inhibitory interneurons in the cortex. Dr. Agmon will combine his expertise with that of Dr. Kawaguchi to study the functional and morphological organization of inhibition with the thalamocortical circuit. This proposal brings together research scientists from two countries working in the area of neuronal anatomy and physiology. The U. S. scientist will have the opportunity to become familiar with research techniques, equipment, and facilities at RIKEN while contributing to the overall research effort. Therefore, this proposal fulfills the objectives of the Program in its exchange and transfer of scientific knowledge through an international collaboration. ***