Engineering nanomaterial interactions with the cell surface

工程纳米材料与细胞表面的相互作用

• 批准号: FT220100092
• 负责人: Prof Megan Lord
• 金额: $ 74.59万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-02-27 至 2027-02-26
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT220100092
• 关键词: Engineering; nanomaterial; interactions; cell; surface

This Fellowship aims to advance understanding of the endothelial cell surface, a key tissue barrier, and its interactions with nanomaterials. Enabled by cross-disciplinary collaboration, it expects to develop knowledge in matrix biology of the cell surface and materials as well as new methods to analyse their interactions. This is expected to unravel causal relationships between nanomaterial features and interactions at the cell surface which will be integrated to engineer optimised materials. This will address the current and critical challenges of nanomaterial technologies in the efficient and targeted interactions with cells with long-term benefits for the consumer, biotechnology and healthcare sectors.

该奖学金旨在促进对内皮细胞表面（一个关键的组织屏障）及其与纳米材料相互作用的理解。通过跨学科合作，它期望开发细胞表面和材料的基质生物学知识以及分析它们相互作用的新方法。这有望解开纳米材料特征和细胞表面相互作用之间的因果关系，这将集成到工程优化材料中。这将解决纳米材料技术在与细胞有效和有针对性的相互作用方面面临的当前和关键挑战，并为消费者、生物技术和医疗保健部门带来长期利益。