The physiological role of P-glycoprotein in the gastrointestinal absorption of cholesterol

P-糖蛋白在胃肠道吸收胆固醇中的生理作用

• 批准号: 206159
• 负责人: Lee Stephen D
• 金额: $ 5.1万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-10-01 至 2011-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=206159&lang=en
• 关键词: Animal Models; Cardiovascular System; Cell Culture Models; Cholesterol Absorption; Cholesterol Excretion; Gastrointestinal Physiology; Knockout Studies; Lipid Biochemistry; Lipid Rafts; Lipid Transport

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among Canadians, accounting for an estimated 36 per cent of premature deaths. The majority of these CVD-related deaths result from ischemic heart disease (insufficient blood supp

心血管疾病是加拿大人发病和死亡的主要原因，估计占过早死亡的36%。这些心血管病相关死亡大多数是由缺血性心脏病（血液供应不足）引起的。