Stereoselective Hydrogenation of Pheromone Precursor Alkynes

阿尔文·韦斯这是与哈萨克斯坦共和国科学院有机催化和电化学研究所的A.M.Pak教授合作的成果。这项工作的目的是控制长链乙炔加氢生成的烯烃异构体的立体专一性。研究了氧化铝、氧化镁或二氧化硅上浸渍的铜和铜-钯，立体选择性与分散性和表面酸性有关。金属交换沸石也可用作催化剂。量子化学(CNDO/2)计算用于指导可能显示所需选择性的条件和催化剂的选择。乙炔的立体选择性还原在许多系统中都有价值，包括生产单体和从风味增强剂到抗生素的各种生物活性分子。在本研究中，制备了可用于害虫控制的信息素前体。

ABSTRACT Alvin Weiss This is collaboration with Professor A. M. Pak of the I nstitute of Organic Catalysis and Electrochemistry of the Academy of Sciences of the Republic of Kazakhstan. The goal of this work is to control the stereospecifity of olefin isomers produced by the hydrogenation of long-chain acetylenes. Copper and copper-palladium impregnated on alumina, magnesia, or silica are studied and stereoselectivity is correlated with dispersion and surface acidity. Metal-exchange zeolites are also used as catalysts. Quantum chemical (CNDO/2) calculations are used to guide selection of conditions and catalysts that might show the desired selectivity. Stereoselective reduction of acetylenes (alkynes) is valuable for a number of systems including production of monomer and a wide variety of biologically active molecules from flavor ehancers to antibiotics. In the present study, the precursors of pheromones useful for insect control are prepared.