Synthesis of the Major Classes of C-Aryl Glycoside Natural Products

主要类别C-芳基糖苷天然产物的合成

• 批准号: 9521055
• 负责人: Kathlyn Parker
• 金额: $ 30万
• 依托单位: Brown University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-07-01 至 1998-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9521055&HistoricalAwards=false
• 关键词: Synthesis; Major; Classes; Aryl; Glycoside

The focus of this research is the use of the concept of `inverse polarity` for the synthesis of a number of important C-aryl glycosides. Among the target compound are C104, deacetylravidomycin and kidamycin, all three of which have important biological properties. With this award, the Synthetic Organic Program is supporting the research of Dr. Kathlyn Parker of the Department of Chemistry at Brown University. Professor Parker will focus her work on the synthesis of several complex C-aryl glycosides, compounds that have important biological properties.

本研究的重点是“逆”概念的运用 极性’，用于合成许多重要的C-芳基糖苷。 目标化合物包括C104、脱乙酰雷维多霉素和基德霉素， 这三种都具有重要的生物学特性。有了这个奖， 有机合成项目支持凯瑟琳博士的研究 布朗大学化学系的帕克说。 教授 帕克将把她的工作重点放在合成几个复杂的C-芳基 糖苷类化合物具有重要的生物学特性。