Organic Ion-Molecule Chemistry

在有机动力学项目的资助下，明尼苏达大学双城分校的Steven R. Kass教授将研究气相中的有机离子-分子反应。一种独特的变温流动余辉-三重四极装置构成了工作的实验基础。在某些情况下，将对同一物种进行溶液研究。结果将补充从头算分子轨道计算。将特别关注反芳离子，单分子重排，以及（特别是远端）取代基对离子反应性和稳定性的影响。这些实验将提供对某些难以捉摸和高度不稳定的反应中间体的基本理解，包括以前没有实验信息的一类。将进行的实验等将提供建立有机化学规则的核心数据，并将从气相到溶液中获得的基本结果外推，其中大多数制备有机化学是完成的，将对理论和潜在的有机化学实践产生重大影响。f8 Û-ªþ + Ûª█ÑOhª‘ +’ª0 Ý +] $ H l +¢D H + ++++++++++++++++++++++++++++++++ R:\WWUSER\TEMPLATE\NORMAL。点

With funding from the Organic Dynamics Program, Professor Steven R. Kass of the University of Minnesota-Twin Cities will study organic ion-molecule reactons in the gas phase. A unique variable temperature flowing afterglow-triple quadrupole aparatus forms the experimental basis for the work. In some cases, solution studies will be performed on the same species. Results will be supplemented with ab initio molecular orbital calculations. Particular attention will be given to antiaromatic ions, unimolecular rearrangements, and the effect of (particularly remote) substituent effects on ion reactivity and stability. These experiments will provide fundamental understanding of certain elusive and highly unstable reactive intermediates, including a class for which no previous experimental information has been available. Experiments such as those which will be performed provide the hard-core data on which the rules of organic chemistry are built, and extrapolation of the basic results obtained in the gas phase to solution, where most preparative organic chemistry is done, will have substantial impact on theory and potentially on practice in organic chemistry. f8 Û-ª þ + Ûª▓ ÑOh ª' +'ª▒0 Ý + ] $ H l + ¢ ╗ D h + ++++++++++++++++++++++++++++++++ R:\WWUSER\TEMPLATE\NORMAL.DOT