Organic Ion-Molecule Chemistry

有了这个奖项，有机和高分子化学计划支持教授史蒂芬R。明尼苏达大学的卡斯说。 该提案中的化学涉及范围很广，是基础研究与实践科学交织在一起的一个例子。 将获得对酶结构和功能，新材料和活性中间体（在几乎所有化学转化中发挥核心作用）的新见解。 更具体地，具有相反电荷位点的化合物（即两性离子）将被探测，氨基酸和肽的反应性将被探索，超酸的性质将被测量，在大气或燃烧过程中形成的瞬态化合物的稳定性将被确定，用于进行化学转化的新试剂将被研究，并且具有根本重要性的异常稳定和不稳定的分子，以及在纳米材料制造中的潜在后果。更广泛的影响。该研究计划涵盖各种活动，因此为培训年轻科学家提供了一个很好的平台。 结果将是重要的化学工业和科学家研究化学和大气污染，并定期纳入？受欢迎吗科学期刊、教科书、参考书和数据库，如NIST网站（www.webbook.nist.gov）。 对蛋白质和酶的工作原理的深入了解也可能导致对人类疾病的新理解和非侵入性检测方法。

With this award, the Organic and Macromolecular Chemistry Program supports the work of Professor Steven R. Kass of the University of Minnesota. The chemistry in this proposal spans a wide range and is an example of basic research intertwined with practical science. New insights into enzyme structure and function, novel materials, and reactive intermediates (which play a central role in almost all chemical transformations) will be obtained. More specifically, compounds with oppositely charged sites (i.e. zwitterions) will be probed, the reactivity of amino acids and peptides will be explored, the properties of superacids will be measured, the stability of transient compounds formed in atmospheric or combustion processes will be determined, new reagents for carrying out chemical transformations will be studied, and unusually stabilized and destabilized molecules of fundamental importance, and potential consequence in the fabrication of nanomaterials, will be investigated.Broader Impacts. This research program spans a diverse range of activities and thus provides an excellent platform for training young scientists. The results will be of importance to the chemical industry and the scientists examining the chemistry and pollution of the atmosphere, and are routinely incorporated into ?popular? scientific journals, textbooks, reference books, and databases such as the NIST website (http://www.webbook.nist.gov). Insights into the workings of proteins and enzymes also may lead to new understanding and noninvasive detection methods of human diseases.