Problems in Self-Assembling Systems

自组装系统中的问题

• 批准号: 9531161
• 负责人: Michael Schick
• 金额: $ 25.8万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-04-01 至 2000-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9531161&HistoricalAwards=false
• 关键词: Problems; Self; Assembling; Systems

9531161 Schick This project is concerned with various aspects of self- assembling systems, such as block copolymers and lipids. Microphase separation will be considered in systems of potential technological importance, such as diblock, triblock and dendritic copolymers. There will also be a study of the ternary mixtures of diblock and homopolymers, an examination of the swollen lamellar phases and the effect of fluctuations on them. The interfacial profiles and their energy of the interfaces between different microphases will be calculated. Finally there will be analysis of the self- assembly effects in biological membranes during electroporation and rupture. %%% A better understanding of self-assembly in polymers is the objective in this grant. The self-assembly involves phase separation in a binary and ternary mixtures and the properties of the interfaces. There are special phases and configurations that are studied for their properties. The technological applications of the systems studied here are in the vast range between detergent and drug transport through the membranes and cells.

9531161 Schick该项目关注自组装系统的各个方面，如嵌段共聚物和脂质。 微相分离将被认为是潜在的技术重要性的系统，如二嵌段，三嵌段和树枝状共聚物。 也将有一个研究的三元混合物的二嵌段和均聚物，检查的溶胀层状相和波动对他们的影响。 计算了不同微相之间的界面轮廓和界面能。 最后分析了电穿孔和破裂过程中生物膜的自组装效应。 更好地理解聚合物中的自组装是本资助的目标。自组装涉及二元和三元混合物的相分离以及界面的性质。 有一些特殊的相和构型是为了它们的性质而研究的。 这里研究的系统的技术应用是在洗涤剂和药物通过膜和细胞的运输之间的广阔范围内。