Separations and Structures Throughout the Chemistry Curriculum: GC/MS

通过购买GC/MS，在各级化学课程中加强了分离和结构的概念。GC/MS允许研究更有趣和相关的主题(如环境中的农药或药物测试)，使更多的学生更容易接触到化学。GC/MS的使用为化学专业的学生提供了越来越重要的技术经验。这些目标是通过从普通化学的简单实验开始实现的，这些实验旨在为学生提供GC/MS方面的培训，同时展示其分析能力的力量。学生分析从糖果或口香糖中提取的化合物，并识别主要的调味剂。通过研究同位素的自然分布，原子结构的概念得到了加强。在有机化学中，学生在获得数据时，会以更复杂的方式使用GC/MS来研究取代二苯甲酮和苯乙酮的裂解过程中的线性自由能关系。本实验强化了课堂上讨论的感应效应和共振效应的概念。他们还使用GC/MS来获得自由基氯化反应的动力学数据。这些实验向学生强调并帮助他们更好地理解动力学和热力学在研究有机反应机理中的重要性。在分析化学课程中，学生学习使用连字符技术对痕量有机物进行定量分析的特殊后果。学生继续在高级课程中使用GC/MS来研究化合物的结构，研究复杂混合物的分离，并为研究反应机理获得数据。该仪器加强了专题课程和学生研究项目。

The concepts of separations and structure are enhanced in the chemistry curriculum at all levels by the purchase of a GC/MS. The GC/MS allows the study of more interesting and relevant topics (such as pesticides in the environment or drug testing), making chemistry more accessible to a wider range of students. Use of the GC/MS provides chemistry majors with experience in an increasingly important technique. These goals are achieved by beginning with simple experiments in General Chemistry that are designed to provide the students with training on the GC/MS while demonstrating the power of its analytical capabilities. Students analyze compounds extracted from candy or chewing gum and identify the major flavorants. The concepts of atomic structure are reinforced by studying the natural distribution of isotopes. In Organic Chemistry, students use the GC/MS in a more sophisticated manner when they obtain data to study the linear free energy relationship in the fragmentation of substituted benzophenones and acetophenones. This experiment reinforces the concepts of inductive and resonance effects that are discussed in class. They also use the GC/MS to obtain kinetic data for the free radical chlorination reaction. These experiments underscore to the students and help them better understand the importance of kinetics and thermodynamics in the study of organic reaction mechanisms. In Analytical Chemistry, students learn the special consequences of using a hyphenated technique to quantitatively analyze trace levels of organics. Students continue to use the GC/MS in upper-level courses to study the structure of compounds, to study the separation of complex mixtures, and to obtain data for the study of reaction mechanisms. The instrument enhances special topics courses and student research projects.