The Na+ Efflux Systems of Alkaliphilic Bacillus firmus OF4

嗜碱坚强芽孢杆菌 OF4 的 Na 流出系统

基本信息

  • 批准号:
    9600555
  • 负责人:
  • 金额:
    $ 5万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    1996
  • 资助国家:
    美国
  • 起止时间:
    1996-09-01 至 1997-08-31
  • 项目状态:
    已结题

项目摘要

*** Li 9505412 This Small Business Innovation Research Phase II project will employ a state-of-the-art fabrication method "Pulsed Laser Deposition (PLD)" to create single crystal layered structures of exotic materials (ferroelectrics and conductive oxide) on micromachined silicon with integrated silicon circuitry. These new fabrication methods and materials will permit the construction of electronic devices and infrared (IR) detectors which are faster, more sensitive and lower in cost than competing commercial technologies. The innovations of the proposed program are: 1) advancing thin-film deposition technology to achieve fully epitaxial growth of ferroelectric films on silicon substrates, by using the highly successful pulsed laser deposition technique; 2) replacing the Pt bottom electrode with the epitaxial conductive oxide material, La0.5Sr0.5CoO3 (LSCO); 3) applying emerging thin-film technology to the fabrication and design of uncooled pyroelectric IR detectors, which are currently made only from bulk pyroelectric materials; 4) achieving exceptional thermal speed performance by using micromachined silicon wafers as substrates; 5) achieving fully epitaxial pyroelectric IR detector arrays on Si, which can be monolithically integrated with Si integrated circuits (ICs). In the Phase I program, the proposers successfully demonstrated the feasibility of the critical component for the multilayer technology. Heterostructures containing five epitaxial thin-film layers, i.e. LSCO / BaTiO3 / LSCO / YBa2Cu307-x / YSZ or LSCO / (Pb, Zr)TiO3 / LSCO / YBa2Cu307-x / YSZ, were deposited on Si(100) substrates by in-situ Pulsed Laser Deposition (PLD). The proposers have fabricated and tested an uncooled pyroelectric detector, based on the novel ferroelectric/conductive oxide heterostructures. The Phase I research has laid down a solid foundation for Phase II. The proposers expect that a prototype electronic device, the pyroelectric infrared detectors or detector arrays, will be developed by the end of the Phase II program. In Phase III, this prototype will be packaged and developed into a commercial product. The development of high-performance, low-cost, uncooled IR detector arrays will address future markets in applications such as: infrared spectroscopy, gas analysis, fire detection, thermal imaging, drivers' aid, pollution monitoring, medical thermograph, missile guidance, night vision, target tracking systems, laser detection and range finders, airborne-spaceborne scanners, space-based astronomy, and IR research. ***
* 李9505412 这个小型企业创新研究第二阶段项目将采用最先进的制造方法“脉冲激光沉积(PLD)”,在集成硅电路的微加工硅上创建奇异材料(铁电体和导电氧化物)的单晶分层结构。这些新的制造方法和材料将使电子设备和红外(IR)探测器的结构比竞争的商业技术更快,更灵敏,成本更低。该计划的创新之处在于:1)利用脉冲激光沉积技术,在硅衬底上实现了铁电薄膜的完全外延生长:2)用外延导电氧化物材料La_(0.5)Sr_(0.5)CoO_3(LSCO)代替Pt底电极; 3)将新兴的薄膜技术应用于非致冷热释电红外探测器的制造和设计,目前这种探测器只能由块状热释电材料制成:4)采用微加工硅片作为衬底,实现了优异的热速度性能; 5)在Si上实现完全外延的热释电IR探测器阵列,其可以与Si集成电路(IC)单片集成。在第一阶段计划中,提案人成功地证明了多层技术关键组件的可行性。采用脉冲激光原位沉积(PLD)技术在Si(100)衬底上制备了LSCO /BaTiO 3/ LSCO /YBa 2Cu 307-x / YSZ或LSCO /(Pb,Zr)TiO 3/ LSCO /YBa 2Cu 307-x / YSZ五层外延薄膜异质结构。提出者已经制造和测试了一个非制冷热释电探测器,基于新的铁电/导电氧化物异质结构。第一阶段的研究为第二阶段奠定了坚实的基础。提议者希望在第二阶段计划结束时开发出一种原型电子设备,即热释电红外探测器或探测器阵列。在第三阶段,该原型将被包装并开发成商业产品。 高性能,低成本,非制冷红外探测器阵列的发展将解决未来市场的应用,如:红外光谱,气体分析,火灾探测,热成像,驾驶员辅助,污染监测,医疗温度记录仪,导弹制导,夜视,目标跟踪系统,激光探测和测距仪,航空航天器,星载扫描仪,天基天文学和红外研究。 ***

项目成果

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Terry Krulwich其他文献

好アルカリ性Bacillus pseudofirmus OF4株の電位駆動型NaチャネルNa_vBPはメチル基受容走化性蛋白質と共局在する
嗜碱性芽孢杆菌OF4菌株电压驱动的Na通道Na_vBP与甲基接受趋化蛋白共定位
  • DOI:
  • 发表时间:
    2005
  • 期刊:
  • 影响因子:
    0
  • 作者:
    藤浪 俊;佐藤 孝子;Terry Krulwich;伊藤 政博
  • 通讯作者:
    伊藤 政博

Terry Krulwich的其他文献

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{{ truncateString('Terry Krulwich', 18)}}的其他基金

The Na+/H Anthiporters of Alkaliphilic Bacillus firmus OF4 and of Bacillus subtilis
嗜碱性芽孢杆菌 OF4 和枯草芽孢杆菌的 Na /H 反转运蛋白
  • 批准号:
    9303183
  • 财政年份:
    1993
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing Grant
The Na+ Cycle of Alkaliphilic Bacilli
嗜碱杆菌的钠循环
  • 批准号:
    9018231
  • 财政年份:
    1991
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
The Na+ Cycle of Extremely Alkalophilic Bacilli
极嗜碱杆菌的钠循环
  • 批准号:
    8919510
  • 财政年份:
    1990
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
The Protonmotive Force and Solute Transport in Alkalophilic and Acidophilic Bacteria
嗜碱和嗜酸细菌中的质子动力和溶质运输
  • 批准号:
    8504395
  • 财政年份:
    1985
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing grant
The Protonmotive Force and Solute Transport in Alkalophilic and Acidophilic Bacteria
嗜碱和嗜酸细菌中的质子动力和溶质运输
  • 批准号:
    8121557
  • 财政年份:
    1982
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing grant
Protonmotive Force and Solute Transport in Alkalophilic and Acidophilic Bacteria
嗜碱和嗜酸细菌中的质子动力和溶质运输
  • 批准号:
    7810213
  • 财政年份:
    1979
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing grant
Anaplerotic Enzymes in Arthrobacter and Other Bacterial Species
节杆菌和其他细菌物种中的回补酶
  • 批准号:
    7725586
  • 财政年份:
    1978
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing grant
Gluconeogenic and Anaplerotic Enzymes in Arthrobacter and Other Bacteria
节杆菌和其他细菌中的糖异生酶和回补酶
  • 批准号:
    7518153
  • 财政年份:
    1976
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant

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Function of the Klebsiella pneumoniae RND efflux systems
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    10525108
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    2022
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多药外排系统的翻译后调控
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职业:可再生化学品的细胞输出和流出系统的系统级识别和表征
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