Neural Mechanisms of Drawing Under Different Load Conditions

不同负载条件下绘图的神经机制

• 批准号: 9604555
• 负责人: James Ashe
• 金额: $ 26.54万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9604555&HistoricalAwards=false
• 关键词: Neural; Mechanisms; Drawing; Under; Different

9604555 Ashe Everyday limb movements can be described both in terms of the forces that the muscles produce and in terms of the more spatial, descriptive aspects of the movement such as trajectory, direction, position, and velocity. The brain controls all aspects of limb movement, but it is not known how the brain codes the different aspects of movement. The basis of this project is the hypothesis that the brain controls both muscle force generated during a movement and the spatial aspects of that movement together by regulating the stiffness (force/position), viscosity (force/velocity) and inertia (force/acceleration) of a moving limb. To test this, the project monitors the activity of cells in the motor control area of the brain during the execution of a trained arm movement performed under different conditions. Sophisticated statistical techniques developed by the experimenters are then used to extract the rules used by cells in this brain area to control arm movements. Potential long-term significance of this work includes the application of the understanding of brain codes for movement to the development of prosthetic devices, the treatment of movement disorders, and the development of robotic systems.

小行星9604555 日常的肢体运动既可以用肌肉产生的力量来描述，也可以用运动的更多空间描述性方面来描述，如轨迹、方向、位置和速度。大脑控制着肢体运动的各个方面，但我们不知道大脑是如何编码运动的不同方面的。该项目的基础是假设大脑通过调节运动肢体的刚度（力/位置）、粘性（力/速度）和惯性（力/加速度）来控制运动过程中产生的肌肉力和该运动的空间方面。为了测试这一点，该项目在不同条件下执行训练手臂运动期间，监测大脑运动控制区域的细胞活动。 然后，实验者开发的复杂的统计技术被用来提取这个大脑区域的细胞用来控制手臂运动的规则。这项工作的潜在长期意义包括将对运动大脑代码的理解应用于假肢设备的开发，运动障碍的治疗以及机器人系统的开发。