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An Automated DNA Sequencer for Molecular Phylogeny and Systematics, Population Genetics, Molecular Evolution, and Development

An Automated DNA Sequencer for Molecular Phylogeny and Systematics, Population Genetics, Molecular Evolution, and Development
用于分子系统学和系统学、群体遗传学、分子进化和发育的自动 DNA 测序仪
批准号:
9604814
负责人:
Claude dePamphilis
金额:
$10.83万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-02-01 至 2000-01-31

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中文摘要
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英文摘要
Support is requested to purchase an ABI Prism 377 automated DNA sequencer to be used as a primary research tool for five molecular and evolutionary biologists in the Biology Department at Vanderbilt University. Our research group currently relies heavily on manual sequencing, but recent research needs and new research developments require the use of high-throughput automated sequencing. The ABI Prism 377, which is capable of sustained, accurate data throughput of up to 10 times what we can now accomplish, would represent a quantum improvement in research capability for our laboratories. The five PIs / Major Users will conduct a series of projects on the ABI377 autosequencer that explore diverse problems in organismal and molecular evolution: 1) Phylogenetic and mechanistic studies of organelle DNA evolution in photosynthetic and nonphotosynthetic plants (dePamph1lis), 2) Molecular phylogenetic studies of species interactions and coevolution (Pellmyr), 3) Evolution of genes underlying circadian clocks in plants and cyanobacteria (Johnson), 4) Organelle DNA polymorphism and the genetics of metapopulations (McCauley), and 5) Evolution of development in chordates (Swalla).
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Digitization PEN: Partnering the Penn State Herbarium (PAC) to Contextualize the Mid-Atlantic Megalopolis
The Amborella Genome: A Reference for Plant Biology
Collaborative Research: From Acorus to Zingiber - Assembling the Phylogeny of the Monocots
DISSERTATION RESEARCH: Single Copy Nuclear Genes in Basal Angiosperms
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