Expression and Function of the LTP-Associated Gene During Learning

[7066 . 64]佩纳·德·奥尔蒂斯长期记忆的形成被认为与大脑细胞的改变有关。这种修饰被认为依赖于这些细胞中基因功能调节的改变。该项目使用分子生物学技术来研究大脑中一个重要部位海马区在获得记忆过程中基因表达的变化。该项目记录了记忆获得过程中基因表达变化的时间过程。然后进行实验，以确定与学习引起的变化有关的基因的DNA序列，然后确定这些基因的产物的功能。这个项目的结果将大大增加对大脑如何存储信息的理解

9706664 Pena de Ortiz The formation of long term memory is though to involve the modification of cells within the brain. Such modification is believed to depend on changes in the regulation of gene function in those cells. This project uses the techniques of molecular biology to investigate changes in gene expression during the acquisition of memory in one important part of the brain termed the hippocampus. The project documents the time course of changes in gene expression that occur as memories are acquired. Experiments then proceed to identify the DNA sequences of genes linked to learning-induced changes, and thereafter the functions of the products of those genes. The results of this project will add significantly to the understanding of how the brain stores information