Insect Cold-Hardiness and Diapause: Regulatory Relationships

昆虫的抗寒性和滞育：调节关系

• 批准号: 9728573
• 负责人: Richard Lee
• 金额: --
• 依托单位: Miami University
• 依托单位国家: 美国
• 项目类别: Continuing grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-02-15 至 2002-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9728573&HistoricalAwards=false
• 关键词: Insect; Cold; Hardiness; Diapause; Regulatory

Lee 9728573 Collaborative research between the PIs' will focus on physiological mechanisms used by insects for overwinter survival. This study examines mechanisms utilized by two types of insects, one that can not tolerate freezing (a flesh fly) and one that tolerates extensive internal freezing (the gall fly larvae). The first part of the project will characterize cold shock (stress) proteins and their genes in relation to their role in cold tolerance. The second part examines the nature of cellular cold hardening and intracellular freeze tolerance. Lastly the PIs' will investigate the role of glycerol in protecting the nervous system against cold shock injury. This work will not only provide an understanding of new mechanisms of cold tolerance, but may also provide new tools both for the disruption of insect pest populations, and for the long-term storage of insects and other organisms at low temperature.

Lee 9728573 PI之间的合作研究将集中在昆虫越冬生存所使用的生理机制上。这项研究考察了两种昆虫利用的机制，一种是不能耐受冰冻的昆虫(肉蝇)，另一种是耐受广泛内部冰冻的昆虫(胆蝇幼虫)。该项目的第一部分将描述冷休克(应激)蛋白及其基因在耐冷性中的作用。第二部分考察了细胞冷硬化和细胞内耐冻性的本质。最后，PI将研究甘油在保护神经系统免受冷休克损伤中的作用。这项工作不仅将提供对耐寒新机制的了解，还可能为害虫种群的破坏以及昆虫和其他生物在低温下的长期储存提供新的工具。