Gas Phase Ion Chemistry

气相离子化学

• 批准号: 9729146
• 负责人: Michael Bowers
• 金额: $ 80.4万
• 依托单位: University of California-Santa Barbara
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-03-01 至 2002-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9729146&HistoricalAwards=false
• 关键词: Gas; Phase; Ion; Chemistry

The Experimental Physical Chemistry Program supports Michael T. Bowers of the University of California-Santa Barbara in his continuing studies of sigma bond activation at transition metal centers. Prof. Bowers will investigate clustering of second row metals with dihydrogen, reactions of first and second row metals with methane and other small alkanes, the role of different ligands in tuning reactivity, and cluster assisted sigma-bond activation. In addition, he will focus on a new effort studying macromolecular systems. He will exploit gas phase H/D exchange as a complementary method for conformational analysis of biologically interesting systems; specifically, he will investigate polymer conformation, folding dynamics and energetics as a function of repeat number. He also plans to study host/guest systems, in particular the influence of solvation on host selectivity. To support the biological studies, Prof. Bowers will construct a bright electrospray based mass spectrometer. Gas phase ion chemistry and the related discipline of mass spectrometry have made huge strides during the past decade, especially in the past five years. Much of this progress is due to technological breakthroughs in detector design, ion sources and the availability of bigger, faster and especially cheaper computers. Further development of this powerful analytical tool as applied to bond activation at metal centers will improve understanding of the behavior of heterogeneous catalysts, used extensively in many industrial processes. Prof. Bower's present effort focusing on macromolecular systems will provide structural information on these larger species.

实验物理化学计划支持迈克尔T。鲍尔斯 加州大学圣巴巴拉分校继续研究 在过渡金属中心的σ键活化。 鲍尔斯教授将 研究第二行金属与二氢的簇合反应， 第一和第二行金属与甲烷和其他小烷烃， 不同配体在调节反应性中的作用，以及簇辅助 σ键激活 此外，他将专注于一项新的努力， 研究大分子系统 他将开发气相H/D交换 作为生物学构象分析的补充方法， 有趣的系统;具体来说，他将研究聚合物 构象，折叠动力学和能量学作为重复的函数 number. 他还计划研究主/客系统，特别是 溶剂化对主体选择性的影响。 为了支持生物学 研究，鲍尔斯教授将构建一个明亮的电喷雾为基础的质量 光谱仪 气相离子化学与质谱相关学科 在过去十年中取得了巨大进步，尤其是在过去 五年 这一进步很大程度上归功于技术突破 在探测器的设计上，离子源的可用性更大，速度更快， 尤其是便宜的电脑。 进一步发展这一强大的 应用于金属中心处的键激活的分析工具将 提高对多相催化剂行为的理解， 广泛应用于许多工业过程。 鲍尔教授目前的努力 对大分子系统的关注将提供以下结构信息： 这些更大的物种。