ERC: Research Center for the Engineering of Living Tissues

ERC：活组织工程研究中心

• 批准号: 9731643
• 负责人: Robert Nerem
• 金额: --
• 依托单位: Georgia Tech Research Corporation
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9731643&HistoricalAwards=false
• 关键词: ERC; Research; Center; Engineering; Living

9731643 NEREM This award initiates the Engineering Research Center for the Engineering of Living Tissues. The lead institution is the Georgia Institute of Technology and the Emory University School of Medicine is a core partner institution. The award funds the first five years of effort under a new cooperative agreement, with a potential duration of ten years. This ERC will address an area of great importance to health and health care at an opportune time. The tissue engineering industry is at a nascent stage, and many of the developments in the field are based on empiricism or art. This center will bring a more fundamental understanding of the underlying biological and engineering principles to the area of tissue engineering, filling the gap that currently exists between academic understanding and industrial reduction to practice. Equally, if not more importantly, this Center will produce well trained engineers with a strong background in the biological and medical sciences who have worked closely with clinical practitioners and industry. This ERC focuses on the design and development of tissue substitutes that replace, enhance or maintain natural tissue function. The Center's research program is organized into three thrusts that represent a continuum of the challenges of tissue engineering: cell technology, cell construct technology (prototype organ or tissues structures) and integration into living systems. Integrated with expertise in medical theory and practice, the ERC will carry out research on the underlying biology and immune response of tissue cells, the application of fundamental engineering design concepts to the growth and function of cell structures or constructs, and the incorporation of these constructs into living systems. This Center promises to produce breakthroughs in both the underlying understanding of tissue function and the technology required for tissue replacement. The two institutions will develop a joint program of bioengineering in support of th e ERC. ERC outreach will involve Spellman College and Morehouse College, local historically Black institutions, and a special program to involve local high school teachers and their students. Industry will be actively involved through a group of firms, representing both emerging start-up and well-established firms. This award is the outcome of the entry of this ERC's pre-proposal in the FY 1997-98 Engineering Research Centers Competition under the ERC Program Announcement, NSF 97-5.

小行星9731643 该奖项启动了生物组织工程的工程研究中心。 牵头机构是格鲁吉亚理工学院，埃默里大学医学院是核心伙伴机构。 该奖项为新合作协议下的前五年努力提供资金，可能持续十年。 这一紧急救济委员会将在适当的时候处理一个对健康和保健极为重要的领域。 组织工程产业正处于萌芽阶段，该领域的许多发展都是基于生物学或艺术。该中心将为组织工程领域带来对基本生物学和工程学原理的更基本理解，填补目前存在于学术理解和工业实践之间的差距。 同样，如果不是更重要的话，该中心将培养训练有素的工程师，他们在生物和医学科学方面具有很强的背景，与临床医生和行业密切合作。 ERC专注于设计和开发替代、增强或维持天然组织功能的组织替代品。 该中心的研究计划分为三个重点，代表了组织工程的挑战：细胞技术，细胞构建技术（原型器官或组织结构）和整合到生命系统中。 ERC将结合医学理论和实践方面的专业知识，对组织细胞的基础生物学和免疫反应进行研究，将基本工程设计概念应用于细胞结构或构建体的生长和功能，并将这些构建体纳入生命系统。 该中心有望在对组织功能的基本理解和组织替代所需的技术方面取得突破。 这两个机构将开发一个生物工程联合项目，以支持ERC。 ERC的推广活动将涉及斯佩尔曼学院和莫尔豪斯学院，当地历史上的黑人机构，以及一个特别计划，涉及当地高中教师和他们的学生。 工业界将通过一批公司积极参与，这些公司既代表新兴的初创公司，也代表成熟的公司。 该奖项是ERC在1997-98财政年度工程研究中心竞赛中根据ERC计划公告NSF 97-5提交的预提案的结果。