IGERT: Stem Cell BIomanufacturing

干细胞生物学发现转化为一系列应用的技术具有巨大的前景，将对社会的广泛领域产生影响；然而，只有在个人接受必要的跨学科专业知识培训以促进该领域的发展时，才能实现这一目标。这项授予佐治亚理工学院的综合性教育和研究培训(IGERT)奖通过创建一个综合教育计划，将干细胞研究的技术创新、商业化和公共政策方面结合在一起，为博士研究生提供这样的培训。作为此次培训的一部分，开展的具体研究项目侧重于开发干细胞分离、鉴定、繁殖和分化所需的标准化和定量方法。将开发可扩展的生物制造实践，以高效地以容易获得的形式生产足够数量的干细胞和衍生品，以满足干细胞的新的治疗和诊断应用的需要。除了培养博士生成为干细胞生物制造领域的领导者的研究和教育活动外，该项目的更广泛影响之一将是为学生提供基于与国际合作伙伴建立的关系的全球科学视角。毕业生将为蓬勃发展的干细胞行业做出贡献，为干细胞影响社会带来新的生物医学和生物技术机会。该计划的一个关键的更广泛的影响和长期目标将是促进代表不足的群体的成员参与干细胞工程。IGERT是一个NSF范围内的项目，旨在应对培养具有跨学科背景、所选学科的深厚知识以及满足未来职业需求所需的技术、专业和个人技能的美国博士科学家和工程师的挑战。该项目旨在通过建立创新的研究生教育和培训新模式，在超越传统学科界限的合作研究的肥沃环境中，催化研究生教育的文化变革。

The transformation of stem cell biology discoveries into technologies for a range of applications has enormous promise to impact a broad spectrum of society; however, achieving this aim will only occur if individuals are trained with the necessary interdisciplinary expertise to facilitate growth of the field. This Integrative Graduate Education and Research Training (IGERT) award to the Georgia Institute of Technology provides such training for Ph.D. graduate students by creating a comprehensive educational program that brings together technological innovation, commercialization, and public policy aspects of stem cell research. The specific research projects conducted as part of this training focus on developing standardized and quantitative methods necessary for stem cell isolation, characterization, propagation, and differentiation. Scalable biomanufacturing practices will be developed to efficiently produce sufficient numbers of stem cells and derivatives in readily accessible formats in order to meet the need for novel therapeutic and diagnostic applications of stem cells. In addition to the research and educational activities to train Ph.D. students to be leaders in the field of stem cell biomanufacturing, one of the broader impacts of this program will be to provide students with a global scientific perspective based upon the established relationships with our international partners. Graduates will contribute to the burgeoning stem cell industry, catalyzing new biomedical and biotechnological opportunities for stem cells to impact society. A key broader impact and long-term objective of the program will be to foster the participation of members of underrepresented groups in stem cell engineering. IGERT is an NSF-wide program intended to meet the challenges of educating U.S. Ph.D. scientists and engineers with the interdisciplinary background, deep knowledge in a chosen discipline, and the technical, professional, and personal skills needed for the career demands of the future. The program is intended to catalyze a cultural change in graduate education by establishing innovative new models for graduate education and training in a fertile environment for collaborative research that transcends traditional disciplinary boundaries.