Incorporating Gas Chromatography/Mass Spectrometry into the Undergraduate Curriculum

该项目将气相色谱质谱仪（GC/MS）纳入整个化学课程。 在介绍性实验课程中，在演示色谱的实验室之后，学生使用GC/MS使用分离材料的保留时间和分子量来识别液体混合物。 在有机化学实验室中，学生学习更多的气相色谱和质谱理论，并使用GC/MS分析他们合成或接收的各种材料。 GC/MS还允许在本课程中进行更广泛的特殊项目。 在分析化学中，学生可以开始独立使用GC/MS。 他们可以开发一种程序来分析土豆中的农药，并分析在模拟空间条件下从材料中排放的气体。 在光谱学课程中，可以使用GC/MS获得的质谱来说明影响质谱的实验参数。 在生物化学实验室，学生使用仪器来确定从天然物质中分离和制备的脂肪酸酯的组成，并使用GC/MS来确定蛋白质的氨基酸组成。 在高级实验室中，GC/MS允许研究级合成产物和更困难的未知物进行充分表征。 该仪器可以促进一些本科生的研究项目，并允许其他项目开始。 可以为当地化学界赞助一系列关于质谱法的研讨会，请当地工业界和当地大学的发言人发言。 *

This project incorporates a gas chromatograph mass spectrometer (GC/MS) throughout the chemistry curriculum. In the introductory laboratory courses, after a laboratory illustrating chromatography, students use the GC/MS to identify a mixture of liquids using the retention times and molecular weights of the separated materials. In organic chemistry laboratory, students learn more of the theory of gas chromatography and mass spectrometry and use GC/MS in the analysis of a variety of materials they synthesize or receive. A GC/MS also permits a wider variety of special projects in this course. In analytical chemistry, students can begin using the GC/MS independently. They can develop a procedure to analyze potatoes for pesticides and a procedure to analyze gases that are emitted from materials in simulated space conditions. In the spectroscopy course, mass spectra taken by GC/MS can be used to illustrate the experimental parameters that affect mass spectra. In biochemistry laboratory, students use the instrument to determine the composition of fatty acid esters isolated and prepared from naturally occurring materials, and they use the GC/MS to determine the amino acid composition of a protein. In senior laboratory, the GC/MS permits research-level synthesis products and more difficult unknowns to be fully characterized. The instrument can further some undergraduate research projects and permit other projects to be started. A series of seminars on mass spectrometry can be sponsored for the local chemistry community using speakers from local industry and local universities. *