Incorporating Gas Chromatography/Mass Spectrometry into the Undergraduate Curriculum

将气相色谱/质谱纳入本科课程

• 批准号: 9751521
• 负责人: Thomas Douglas
• 金额: $ 2.87万
• 依托单位: St. John Fisher College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-01 至 1999-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9751521&HistoricalAwards=false
• 关键词: Incorporating; Gas; Chromatography; Mass; Spectrometry

This project incorporates a gas chromatograph mass spectrometer (GC/MS) throughout the chemistry curriculum. In the introductory laboratory courses, after a laboratory illustrating chromatography, students use the GC/MS to identify a mixture of liquids using the retention times and molecular weights of the separated materials. In organic chemistry laboratory, students learn more of the theory of gas chromatography and mass spectrometry and use GC/MS in the analysis of a variety of materials they synthesize or receive. A GC/MS also permits a wider variety of special projects in this course. In analytical chemistry, students can begin using the GC/MS independently. They can develop a procedure to analyze potatoes for pesticides and a procedure to analyze gases that are emitted from materials in simulated space conditions. In the spectroscopy course, mass spectra taken by GC/MS can be used to illustrate the experimental parameters that affect mass spectra. In biochemistry laboratory, students use the instrument to determine the composition of fatty acid esters isolated and prepared from naturally occurring materials, and they use the GC/MS to determine the amino acid composition of a protein. In senior laboratory, the GC/MS permits research-level synthesis products and more difficult unknowns to be fully characterized. The instrument can further some undergraduate research projects and permit other projects to be started. A series of seminars on mass spectrometry can be sponsored for the local chemistry community using speakers from local industry and local universities. *

本项目将气相色谱仪-质谱计（GC/MS）贯穿于整个化学课程。在实验入门课程中，学生将通过实验讲解色谱法，使用GC/MS通过分离物质的保留时间和分子量来鉴别混合液体。在有机化学实验室中，学生学习了更多的气相色谱和质谱理论，并使用GC/MS对他们合成或接收的各种材料进行分析。在本课程中，GC/MS还允许更广泛的特殊项目。在分析化学中，学生可以开始独立使用GC/MS。他们可以开发一种程序来分析土豆中的农药，以及一种程序来分析模拟空间条件下物质释放的气体。在光谱学过程中，可以用GC/MS的质谱来说明影响质谱的实验参数。在生物化学实验室中，学生使用该仪器测定从天然物质中分离和制备的脂肪酸酯的组成，并使用GC/MS测定蛋白质的氨基酸组成。在高级实验室，GC/MS可以对研究级合成产物和更困难的未知物进行全面表征。该仪器可以进一步一些本科研究项目，并允许其他项目开始。可以为当地化学团体主办一系列关于质谱法的研讨会，邀请来自当地工业界和当地大学的演讲者。＊