High Field NMR Across the Undergraduate Curriculum

高场核磁共振贯穿本科课程

• 批准号: 9751691
• 负责人: Julia Baker
• 金额: $ 9.89万
• 依托单位: Winthrop University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-01 至 1999-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9751691&HistoricalAwards=false
• 关键词: Field; NMR; Across; Undergraduate; Curriculum

The 300 MHz Fourier transform NMR spectrometer is used in a wide range of courses to improve the quality of education for students majoring in chemistry, biology, human nutrition, and medical technology. the objectives of this project are: to excite students about chemistry by exposing them to this powerful tool for structure determination, to train them in the theory, methods, and application of modern NMR spectroscopy, and to combine this structural tool with molecular modeling to give them a broader perspective of chemical science. The NMR spectrometer is first introduced to students in the General Chemistry cooperative laboratory program. Sophomore organic students use the instrument to obtain proton and C-13 spectra for product analysis and are also introduced to two-dimensional NMR through a COSY experiment. Students then use variable temperature NMR in the inorganic laboratory to explore the structural and fluxional behavior of inorganic systems. In the physical chemistry laboratory, students use variable temperature NMR to obtain kinetic and thermodynamic data for the internal rotations in N,N-dimethylacetamides. In instrumental analysis, students use the instrument to study the relationships between time and frequency domain spectra as well as signal averaging and digital filtering. Emphasis is placed on using the NMR in conjunction with molecular modeling to provide the opportunity for students to explore the relationship between structure and spectra. *

300 MHz傅里叶变换核磁共振光谱仪用于广泛的课程，以提高化学，生物，人类营养和医疗技术专业学生的教育质量。 本计画的目标是：让学生接触到这一强有力的结构测定工具，激发他们对化学的兴趣，训练他们现代核磁共振光谱学的理论、方法和应用，并将联合收割机这一结构工具与分子模拟相结合，使他们对化学科学有更广阔的视野。 NMR光谱仪首先介绍给学生在普通化学合作实验室计划。 大二有机学生使用该仪器获得质子和C-13光谱进行产品分析，并通过COSY实验介绍二维NMR。 然后，学生在无机实验室中使用变温核磁共振来探索无机系统的结构和流动行为。 在物理化学实验室，学生使用变温核磁共振获得N，N-二甲基乙酰胺内旋转的动力学和热力学数据。 在仪器分析中，学生使用仪器研究时域和频域光谱之间的关系以及信号平均和数字滤波。 重点放在使用核磁共振结合分子建模，为学生提供机会，探索结构和光谱之间的关系。 *