Solid-State NMR Across the Periodic Table: Methods and Applications

整个元素周期表的固态核磁共振：方法和应用

• 批准号: RGPIN-2016-06642
• 负责人: Schurko, Robert
• 金额: $ 6.63万
• 依托单位: University of Windsor
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632273
• 关键词: Solid; State; NMR; Across; Periodic

Solid-state NMR (SSNMR) spectroscopy is the most powerful technique for the characterization of molecular-level structure and dynamics. NMR spectra are more sensitive to structural differences and changes than any other type of spectroscopy, which makes NMR invaluable for use in chemistry, biochemistry, physics and materials science. However, its major shortcoming is its sensitivity: since NMR is a very low energy spectroscopy, it can take a long time to acquire spectra with high signal-to-noise (S/N) ratios. Until recently, it was very difficult (or in some cases impossible) to acquire NMR spectra for many of the nuclides of the elements in the periodic table (about 80%) - these are collectively known as unreceptive NMR nuclides. Indeed, one of the holy grails of NMR is to solve the problem of low sensitivity, which would open NMR experimentation to a much broader range of materials, as well as reducing the time frames of conventional NMR experiments.

固体核磁共振谱是表征分子水平结构和动力学的最强大的技术。核磁共振谱对结构差异和变化比任何其他类型的光谱学都更敏感，这使得核磁共振在化学、生物化学、物理和材料科学中的应用非常宝贵。然而，它的主要缺点是它的灵敏度：由于核磁共振是一种非常低的能量光谱，它可能需要很长时间才能获得高信噪比(S/N)的光谱。直到最近，要获得元素周期表中许多元素(约80%)的核磁共振谱是非常困难的(或在某些情况下是不可能的)--这些核素统称为不可接受的核磁共振核素。事实上，核磁共振的圣杯之一是解决低灵敏度的问题，这将使核磁共振实验适用于更广泛的材料，并缩短传统核磁共振实验的时间框架。