Optimization, Scale-Up and Robustness of Protein Ion Exchange Chromatography
Optimization, Scale-Up and Robustness of Protein Ion Exchange Chromatography
批准号:
9813801
负责人:
Steven Cramer
金额:
$16.0万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-11-01 至 2000-10-31
中文摘要
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英文摘要
This grant is awarded through the Separations and Purification program sub-element of the Interfacial, Transport and Separations program of the Chemical and Transport Systems Division. The principal investigator is Dr. Steven Cramer at RPI. The proposed research concerns the study of a technique called preparative ion-exchange chromatography to efficientlu purify proteins. The objectives are to develop a protein adsorption model based upon experimental adsorption data and the use of this model tooptimize system performance. The proposed research suggests various approaches for advancing the state of knowledge in this area and encompasses a good blend of theoretical studies experimental work and modeling of the data.
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Preferred binding regions for highly selective and orthogonal multimodal protein separations
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High Selectivity and Capacity Bioseparations using Hybrid Displacement-Multimodal Systems
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依托单位:
Travel Grant for Sixth Mediterranean Chemical Engineering Conference in Belek, Antalya, Turkey (March 7-12, 2010)
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批准号:1012114
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GOALI: Industrial Implementation of Smart Biopolymers for Antibody Purification
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Improving the Understanding and Application of Multi-Modal Chromatography
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Chemically Selective Displacers for Protein Purification
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批准号:0730830
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Travel Grant for Fifth Mediterranean Chemical Engineering Conference
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依托单位:
Travel Grant for Fourth Mediterranean Chemical Engineering Conference for Collaborative Research; Dead Sea, Israel, January 9-12, 2006
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资助金额:$0.0万
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财政年份:2005
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Selective Filling of Nanostructured Packings for Chromatographic Chip Systems
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批准号:0522656
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资助金额:$0.0万
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财政年份:2005
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依托单位:
Prediction and Understanding of Protein Affinity
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批准号:0418413
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资助金额:$157.76万
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财政年份:2004
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依托单位:
Quantitative Combinatorial Design of Displacers and Affinity Ligands
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批准号:0079436
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资助金额:$69.17万
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财政年份:2001
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依托单位:
Research on Advanced Technologies for Housing: The Interdependency of the Fire Protection Membrane and the Structural Response of Light-Frame Engineered Wood Floors and Ceilings
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批准号:0080293
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项目类别:Standard Grant
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资助金额:$14.1万
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财政年份:2000
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依托单位:
1999 Gordon Conference on Reactive Polymers, Ion Exchangers and Adsorbents to be held July 18-23, 1999 in Henniker, New Hampshire
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批准号:9904267
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项目类别:Standard Grant
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资助金额:$1.0万
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财政年份:1999
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依托单位:
Hydrophobic Displacement Chromatography of Proteins
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批准号:9810794
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项目类别:Continuing Grant
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资助金额:$23.68万
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财政年份:1998
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批准号:9416921
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资助金额:$18.95万
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财政年份:1995
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负责人:Steven Cramer
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依托单位:
Design of Low Molecular Weight Displacers for Protein Purification by Ion Exchange Displacement Chromatography
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批准号:9412737
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项目类别:Continuing Grant
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资助金额:$39.07万
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财政年份:1994
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负责人:Steven Cramer
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依托单位:
Displacement Chromatography of Proteins: Identification of Critical Displacer Properties and Development of Novel Nontoxic Displacers
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项目类别:Standard Grant
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资助金额:$16.0万
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财政年份:1991
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国内基金
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