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Optimization, Scale-Up and Robustness of Protein Ion Exchange Chromatography

Optimization, Scale-Up and Robustness of Protein Ion Exchange Chromatography
蛋白质离子交换色谱的优化、放大和稳健性
批准号:
9813801
负责人:
Steven Cramer
金额:
$16.0万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-11-01 至 2000-10-31

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中文摘要
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英文摘要
This grant is awarded through the Separations and Purification program sub-element of the Interfacial, Transport and Separations program of the Chemical and Transport Systems Division. The principal investigator is Dr. Steven Cramer at RPI. The proposed research concerns the study of a technique called preparative ion-exchange chromatography to efficientlu purify proteins. The objectives are to develop a protein adsorption model based upon experimental adsorption data and the use of this model tooptimize system performance. The proposed research suggests various approaches for advancing the state of knowledge in this area and encompasses a good blend of theoretical studies experimental work and modeling of the data.
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Preferred binding regions for highly selective and orthogonal multimodal protein separations
  • 批准号:
    1704745
  • 项目类别:
    Standard Grant
  • 资助金额:
    $32.65万
  • 财政年份:
    2017
  • 负责人:
    Steven Cramer
  • 依托单位:
Travel Grant for Eighth Mediterranean Chemical Engineering Conference to be held in Israel in 2014
  • 批准号:
    1248189
  • 项目类别:
    Standard Grant
  • 资助金额:
    $4.8万
  • 财政年份:
    2012
  • 负责人:
    Steven Cramer
  • 依托单位:
Molecular Engineering of Multiple Weak Interactions for High Selectivity Bioseparations
  • 批准号:
    1160039
  • 项目类别:
    Standard Grant
  • 资助金额:
    $34.0万
  • 财政年份:
    2012
  • 负责人:
    Steven Cramer
  • 依托单位:
Travel Grant for Seventh Mediterranean Chemical Engineering Conference, Greece
  • 批准号:
    1137546
  • 项目类别:
    Standard Grant
  • 资助金额:
    $4.8万
  • 财政年份:
    2011
  • 负责人:
    Steven Cramer
  • 依托单位:
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基于热量传递的传统固态发酵过程缩小(Scale-down)机理及调控
  • 批准号:
    22108101
  • 项目类别:
    青年科学基金项目(C类)
  • 资助金额:
    30.0万元
  • 批准年份:
    2021
  • 负责人:
    靳光远
  • 依托单位:
基于Multi-Scale模型的轴流血泵瞬变流及空化机理研究
  • 批准号:
    31600794
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    22.0万元
  • 批准年份:
    2016
  • 负责人:
    荆腾
  • 依托单位:
针对Scale-Free网络的紧凑路由研究