Small Ring-Mediated Organic Synthesis

本研究的重点是利用Kulinkovich环丙烷反应的一种变体来获得杂取代环丙烷。所取代的环丙烷将作为几种有机化合物的合成中间体。靶分子包括中等大小的碳环、三醌和功能化生物碱。有了这个新的奖项，有机和大分子化学项目支持了阿拉巴马大学化学系Jin K. Cha博士的研究。查教授将致力发展以三元环固有反应性为基础的合成方法。该方法将用于合成有趣的天然产物。

The focus of this research is the use of a variant of the Kulinkovich cyclopropanation reaction to afford hetero-substituted cyclopropanes. The substituted cyclopropanes will serve as synthetic intermediates for the production of several classes of organic compounds. Among the target molecules are medium sized carbocycles, triquinanes and functionalized alkaloids.With this new award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. Jin K. Cha of the Department of Chemistry at the University of Alabama. Professor Cha will focus his work on developing synthetic methodology which relies on the inherent reactivity of three membered rings. The methodology will be used to synthesize interesting natural products.