POWRE: Evolution of Plant Resistance Genes

POWRE：植物抗性基因的进化

• 批准号: 9870516
• 负责人: Georgiana May
• 金额: $ 8万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-15 至 2000-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9870516&HistoricalAwards=false
• 关键词: POWRE; Evolution; Plant; Resistance; Genes

9870516 May This research will analyze the importance of molecular rearrangements in generating new alleles at the N locus, a complex viral resistance locus in the Solanaceae. Analysis of the evolutionary importance of rearrangements will address the question of how the genomic architecture of plants might be organized to provide continued resistance to microbial pathogens. In these analyses, the investigator will take advantage of a strong functional selection for altered resistance alleles to recover rearrangements at N in Solanaceae species. Comparing these results to the structure of the N locus in related species within the Solanaceae will allow assessment of the evolutionary importance of rearrangements in generating new N genes and alleles. Understanding the molecular evolutionary interactions of host plants and their associated microorganisms is essential to developing sustainable agricultural systems with low ecological impact and can define novel approaches to plant protection.

本研究将分析茄科复杂病毒抗性位点N位点分子重排在产生新等位基因中的重要性。对重排的进化重要性的分析将解决植物的基因组结构如何组织以提供对微生物病原体的持续抗性的问题。在这些分析中，研究者将利用对改变抗性等位基因的强大功能选择来恢复茄科物种在N上的重排。将这些结果与茄科相关物种的N位点结构进行比较，将有助于评估重排在产生新的N基因和等位基因中的进化重要性。了解寄主植物及其相关微生物的分子进化相互作用对于开发低生态影响的可持续农业系统至关重要，并且可以确定植物保护的新方法。