CAREER: Cycloaromatization Approach to Graphite Oligomers

安东尼教授的研究重点是电子器件用有机材料的设计和合成。合成工作包括通过烷基萘和-噻吩的衍生化、环化和芳构化制备石墨低聚物。所采用的反应特别包括芳烃的伯格曼环合反应。目标分子是具有各种形状的多芳香族化合物，其物理性质是一些猜测的问题。安东尼教授对测试这些新材料作为场效应晶体管（FET）特别感兴趣。安东尼教授的课堂目标是通过将学生置于他们需要和想要发现解决特定问题所需知识的情境中，激励他们成为更好的学习者。例如，指导学生了解酶活性位点中官能团的性质将使具有互补官能团的“药物”分子的配方成为可能。学生们可能想知道如何合成他们自己的“药物”分子，这将引导他们进入有机合成转化的华丽舞台。高级课程的发展包括结合最新的超分子和材料化学。有了这个职业奖，合成有机项目支持肯塔基大学化学系的约翰·安东尼博士的研究和教育活动。安东尼博士的研究重点是在分子水平上创造出具有精确大小和形状的石墨状结构。在构成这些分子的材料的几种应用中，像场效应晶体管这样的电子设备是最令人兴奋的。安东尼教授的教学努力依靠新方法让学生负责自己的学习，使用基于学生设计药物分子和计划其合成的挑战的策略。高级课程将通过最新材料和超分子化学的注入而充满活力。

Professor Anthony's research focuses on the design and synthesis of organic materials for electronic devices. The synthetic work involves the preparation of graphite oligomers by the derivatization, cyclization, and aromatization of alkynylnaphthalenes and -thiophenes. The reactions to be employed include particularly the Bergman cyclization of arenediynes. The target molecules are polyaromatic compounds having a variety of shapes, whose physical properties are a matter of some conjecture. Professor Anthony is particularly interesting in testing these new materials as FET's (Field-Effect Transistors). The classroom goals of Professor Anthony are to motivate students to become better learners by putting them in situations where they will need -- and want -- to uncover the knowledge required to solve a particular problem. For instance, guiding the student through the properties of functional groups in an enzyme active site will enable the formulation of a "drug" molecule having complementary functional groups. The students then might wonder how to synthesize their (own) "drug" molecule, which leads them into the panoply of organic synthetic transformations. Upper level course development includes incorporation of the latest supramolecular and materials chemistry.With this CAREER award, the Synthetic Organic Program supports the research and educational activities of Dr. John Anthony of the Chemistry Department of the University of Kentucky. Dr. Anthony's research efforts center on the creation of graphite-like structures on a molecular level that have exacting sizes and shapes. Of the several applications of materials that make up these molecules, electronic devices such as field-effect transistors are among the most exciting. Professor Anthony's teaching endeavors rely on new ways to put the student in charge of their own learning, using strategies based on student design of a pharmaceutical molecule and the challenge of planning its synthesis. Upper-level curricular offerings will be invigorated by an infusion of the latest materials and supramolecular chemistry.