CAREER: Synthesis of Metallo-Dendrimers Using Metallo-Phosphoramidites

有了这一职业奖，有机和高分子化学项目支持了杜克大学化学系的Mark W.Grinstaff博士的工作。本研究旨在开发一种新的自动化固相方法来合成新型金属组合物和金属树枝状大分子，并系统地研究这些纳米结构中的能量/电子转移反应。要研究的变量包括给体和受体之间的距离、热力学推动力、聚合物组成和聚合物序列。在这个项目中形成的理解可以在生物化学、药理学、生物学和工程学中使用，包括将太阳能转化为储存的化学能量。这项工作的教育部分包括大学化学实验室的高中生实践经验，以及基于固态材料的新的高级普通化学课程。与PI合作的学生将在金属有机合成、聚合物表征、电化学和光化学领域获得宝贵的技能。

With this CAREER award the Organic and Macromolecular Chemistry Program supports the work of Dr. Mark W. Grinstaff of the Department of Chemistry at the Duke University. The research aims to develop a new automated solid-phase method for the synthesis of novel metallo-assemblies and metallo-dendrimers, and to systematically study the energy/electron transfer reactions in these nanostructures. Variables to be investigated include distance between donors and acceptors, thermodynamic driving force, polymer composition, and polymer sequence. The understanding developed in this project could find uses in biochemistry, pharmacology, biology and engineering, including the conversion of solar energy into stored chemical energy.The educational part of the work includes hands-on experiences for high school students in university chemistry laboratories, and a new advanced general chemistry course based on solid-state materials. Students working with the PI will gain valuable skills in the areas of metallo-organic synthesis, polymer characterization, electro chemistry, and photochemistry.