Synthesis of metallo-peptide nanotubes

纳米管可用于小分子的选择性识别和组装、选择性反应以及利用其空穴传输小分子，因此是一个很有吸引力的纳米尺度的模体。在这项工作中，我们设计了一种分散的超分子纳米管，它由金属离子和三个具有外围双(羟基吡喃酮)型配体的低聚脲组成，有望与方形平面金属离子如Cu^&lt；2&gt；和Pd^&lt；2&gt；形成更平坦的[3 3]大环金属配合物。UV-Vistitration和ESI-TOF-MS测量表明，在DBU存在下，含有两个外围双(羟基吡喃酮)配体的尿素在甲醇中与Cu2&gt；形成离散的三聚体组装。

Nanotube is an attractive nanoscale motif since it can be used for selective recognition and assembly, selective reaction, and transport of small molecules utilizing its cavity. In this work, we have designed a descrete supramolecular nanotube consisted of metal ions and three oligoureas having peripheral bis(hydroxypyrone)-type ligands, which is expected to form planer [3+3] macrocyclic metal complexes with square planar metal ions such as Cu^<2+> and Pd^<2+>. UV-Vistitration and ESI-TOF MS measurement revealed that an urea containing two peripheral bis(hydroxypyrone) ligands formed a discrete trimeric assembly via complexation with Cu^<2+> in MeOH in the presence of DBU.