Synthesis of metallo-peptide nanotubes

纳米管是一种有吸引力的纳米基序，因为它可以用于选择性识别和组装，选择性反应，以及利用其空腔运输小分子。在这项工作中，我们设计了一种由金属离子和三种具有外周双（羟基吡啶酮）型配体的低聚脲组成的超分子纳米管，该纳米管有望与方形平面金属离子（如Cu^<2+>和Pd^<2+>）形成平面[3+3]大环金属配合物。紫外光谱和ESI-TOF质谱分析表明，在DBU存在的情况下，尿素与Cu^<2+>在MeOH中络合形成离散的三聚体。

Nanotube is an attractive nanoscale motif since it can be used for selective recognition and assembly, selective reaction, and transport of small molecules utilizing its cavity. In this work, we have designed a descrete supramolecular nanotube consisted of metal ions and three oligoureas having peripheral bis(hydroxypyrone)-type ligands, which is expected to form planer [3+3] macrocyclic metal complexes with square planar metal ions such as Cu^<2+> and Pd^<2+>. UV-Vistitration and ESI-TOF MS measurement revealed that an urea containing two peripheral bis(hydroxypyrone) ligands formed a discrete trimeric assembly via complexation with Cu^<2+> in MeOH in the presence of DBU.