New Chemistry of Phosphatrane Bases and of Disilanes

教授约翰Verkade，化学系，爱荷华州州立大学是由无机，生物无机，和有机物计划的化学部的研究到自由基硅化学和二级研究的磷杂三环反应性的支持。热形成的硅烷自由基将是用于通过炔环三聚形成芳族分子的试剂。一系列的炔将被调查，以确定取代基的大小和电子性质的范围，环三聚过程可以容忍。将评估将两种不同的炔引入芳族产物中以及使用各种乙硅烷和其他第14族化合物的可能性。通过乙硅烷与化学计量量的炔的反应将形成一系列二硅环系统，并将用于生产氧桥连的二硅环己二烯聚合物。研究的一小部分将针对手性和新型磷杂三环超碱的合成。“炔三聚是一种非常有用的转化，将乙炔转化为芳族分子。最简单的例子是乙炔环化为苯。由于复杂的芳族分子在整个自然界中被发现，药物，制备它们的新方法是非常重要的。这项研究将针对一类硅化合物，可以促进三聚。还将制备一组含有两个硅原子的环状分子。这些将被用作前体，以形成新的聚合物，这些聚合物将比它们类似的有机硅聚合物更坚固。

Professor John Verkade, Chemistry Department, Iowa State University is supported by the Inorganic, Bioinorganic, and Organometallic Program of the Chemistry Division for investigations into free radical silicon chemistry and secondary studies of the phosphatrane reactivity. Thermally formed silane free-radicals will be reagents for the formation of aromatic molecules by alkyne cyclotrimerization. A range of alkynes will be investigated to define the range in substituent size and electronic properties that the cyclotrimerization process can tolerate. The possibility of incorporating two different alkynes into the aromatic product and of using various disilanes and other group 14 cogners will be evaluated. A series of disilicon ring systems will be formed by reactions of disilanes with stoichiometric amounts of alkynes and will be used to produce oxygen bridged disilcyclohexandiene polymers. A minor portion of the investigation will target the synthesis of chiral and novel phosphatrane "superbases." Alkyne trimerization is an extremely useful transformation that converts acetylenes into aromatic molecules. The simplest example is the cyclization of acetylene to benzene. Since complex aromatic molecules are found throughout nature and are encountered in many, e.g., pharmaceuticals, new methods for preparing them are very significant. This study will target a class of silicon compounds that can facilitate the trimerization. A set of cyclic molecules that contain two silicon atoms will also be prepared. These will be used as precursors to form new polymers that will be more robust than the silicone polymers, which they resemble.