Contruction of a Biomolecular Motor-Powered Nanomechanical Device

与分子生物学和纳米制造技术相关的科学进步的融合现在首次提供了工程功能混合有机/无机纳米机械系统的潜力。F1 -ATPase生物分子马达能够产生100 pN的力，计算的空载转速为17转/秒，直径小于12纳米。这些特征与当前纳米机械结构的工程特征一致。因此，本提案的目标是生产一种由生物分子马达f1 - atp酶驱动的纳米机械装置。预计这一努力将产生一种设备，该设备将展示用于创建新型混合有机/无机设备的技术

9907033MontemagnoA confluence in scientific advancements associated with molecular biology and nanofabrication technology now offer, for the first time, the potential of engineering functional hybrid organic/inorganic nanomechanical systems. The F1 -ATPase biomolecular motor is capable of generating a force 100 pN, has a calculated no-load rotational velocity of 17 r.p.s., and a diameter of less than 12 nm. These characteristics are consistent with the engineering features associated with current nanomechanical structures. Thus, the objective of this proposal is to produce a nanomechanical device that is powered by the biomolecular motor, F1-ATPase. It is anticipated that this effort will result in a device that will demonstrate the technology for creating a new class of hybrid organic/inorganic devices.***