Contruction of a Biomolecular Motor-Powered Nanomechanical Device

生物分子马达驱动的纳米机械装置的构建

基本信息

项目摘要

9907033MontemagnoA confluence in scientific advancements associated with molecular biology and nanofabrication technology now offer, for the first time, the potential of engineering functional hybrid organic/inorganic nanomechanical systems. The F1 -ATPase biomolecular motor is capable of generating a force 100 pN, has a calculated no-load rotational velocity of 17 r.p.s., and a diameter of less than 12 nm. These characteristics are consistent with the engineering features associated with current nanomechanical structures. Thus, the objective of this proposal is to produce a nanomechanical device that is powered by the biomolecular motor, F1-ATPase. It is anticipated that this effort will result in a device that will demonstrate the technology for creating a new class of hybrid organic/inorganic devices.***
9907033 MontemagnoA汇合在科学进步与分子生物学和纳米纤维技术现在提供,第一次,工程功能混合有机/无机纳米机械系统的潜力。F1 -ATP酶生物分子马达能够产生100 pN的力,具有17 r.p.s.的计算空载旋转速度,并且直径小于12纳米。这些特征与当前纳米机械结构相关的工程特征一致。因此,本提案的目的是生产由生物分子马达F1-ATP酶提供动力的纳米机械装置。预计这一努力将导致一种设备,该设备将展示用于创建新型混合有机/无机设备的技术。

项目成果

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Carlo Montemagno其他文献

Enzymatic conversion of lactose into galacto-oligosaccharides: The effect of process parameters, kinetics, foam architecture, and product characterization
  • DOI:
    10.1016/j.jfoodeng.2017.11.015
  • 发表时间:
    2018-04-01
  • 期刊:
  • 影响因子:
  • 作者:
    Ehsan Jenab;Mehdi Omidghane;Paolo Mussone;Daniel Hernandez Armada;Jonathan Cartmell;Carlo Montemagno
  • 通讯作者:
    Carlo Montemagno
Electrophysiological Method for Quantification of the Number of phi29 DNA Packaging Nanopore in Planar Bilayer Membrane
  • DOI:
    10.1016/j.bpj.2009.12.3273
  • 发表时间:
    2010-01-01
  • 期刊:
  • 影响因子:
  • 作者:
    Peng Jing;Anne P. Vonderheide;Fazin Haque;Carlo Montemagno;Peixuan Guo
  • 通讯作者:
    Peixuan Guo
Unidirectional Translocation of DNA Through the Phi29 Connector Channel
  • DOI:
    10.1016/j.bpj.2010.12.1132
  • 发表时间:
    2011-02-02
  • 期刊:
  • 影响因子:
  • 作者:
    Peng Jing;Farzin Harque;Dan Shu;Carlo Montemagno;Peixuan Guo
  • 通讯作者:
    Peixuan Guo
Metabolism of 2,4,6-trinitrotoluene by aPseudomonas consortium under aerobic conditions
  • DOI:
    10.1007/bf01571053
  • 发表时间:
    1994-03-01
  • 期刊:
  • 影响因子:
    2.600
  • 作者:
    Ramaraj Boopathy;John Manning;Carlo Montemagno;Charles Kulpa
  • 通讯作者:
    Charles Kulpa
GP10 of Bacteriophage Phi29 Exhibits ATPase Activity
  • DOI:
    10.1016/j.bpj.2008.12.2152
  • 发表时间:
    2009-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Julia L. Jones;David Wendell;Carlo Montemagno
  • 通讯作者:
    Carlo Montemagno

Carlo Montemagno的其他文献

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{{ truncateString('Carlo Montemagno', 18)}}的其他基金

SGER Cooperative Education for Research Careers
SGER 研究职业合作教育
  • 批准号:
    0649914
  • 财政年份:
    2006
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
SGER: Excitable Vesicles - A New Platform
SGER:可兴奋囊泡 - 一个新平台
  • 批准号:
    0436265
  • 财政年份:
    2004
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
Construction of nanosyringe arrays for inserting bimolecular motor-powered nanodevices in living cells
用于在活细胞中插入双分子电机驱动的纳米器件的纳米注射器阵列的构建
  • 批准号:
    0004499
  • 财政年份:
    2001
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
Constructing Nanoscale Molecule Sorters Powered by F1-ATPase Motors
构建由 F1-ATPase 电机驱动的纳米级分子分选机
  • 批准号:
    0084732
  • 财政年份:
    2000
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing grant

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通过外部环境的控制自组织生物分子运动网络的形态控制和功能出现
  • 批准号:
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Development of biomolecular motor based autonomous molecular-robots and its potential application
基于生物分子马达的自主分子机器人的研制及其潜在应用
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Creating a biomolecular motor that moves on artificial tracks
创造在人造轨道上移动的生物分子马达
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    2018
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Rational design of a novel power system from biomolecular motor
新型生物分子电机动力系统的合理设计
  • 批准号:
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    2018
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Single Molecule Motion Analysis of Biomolecular Motor Kinesin in an Active Fluctuation Environment
主动波动环境中生物分子运动驱动蛋白的单分子运动分析
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    2015
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Study on the roles of internal and external factors in active self-organization of biomolecular motor
内外部因素在生物分子运动主动自组织中的作用研究
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    23681019
  • 财政年份:
    2011
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    $ 5万
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Biomolecular Motor Smart Microarrays: Self-Contained, High-Throughput, Ultrasensitive Multiplexed Biomolecular Sensing
生物分子马达智能微阵列:独立、高通量、超灵敏的多重生物分子传感
  • 批准号:
    0966723
  • 财政年份:
    2010
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    $ 5万
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Simulation study of biomolecular motors: Structural analysis of regulation mechanisms of chemical reaction by motor movements
生物分子马达模拟研究:马达运动调节化学反应机制的结构分析
  • 批准号:
    22370057
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    2010
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    $ 5万
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    Grant-in-Aid for Scientific Research (B)
Integrated motor protein-based nano-devices for biomolecular transport
用于生物分子运输的基于运动蛋白的集成纳米装置
  • 批准号:
    0901303
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    2009
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    $ 5万
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NIRT: Biomolecular-Scale Nanofabrication for Investigation of Signaling, Motility, and Motor Protein Complexes
NIRT:用于研究信号传导、运动性和运动蛋白复合物的生物分子规模纳米加工
  • 批准号:
    0507086
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