课题基金 / 基金详情

SBIR Phase I: Expression Pattern Screening for Agriculture Genomics

SBIR Phase I: Expression Pattern Screening for Agriculture Genomics
SBIR 第一阶段:农业基因组表达模式筛选
批准号:
9961034
负责人:
Richard Kris
金额:
$10.0万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-01-01 至 2000-06-30

项目摘要

项目成果

Richard Kris的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
This Small Business Innovation Research Phase I project proposes to develop a high throughput multiple mRNA assay for screening large numbers of compounds to discover potential compounds that affect patterns of gene expression in plant tissue. The expression for a group of genes of interest and control genes can be tested all at once within each well of a 96-well plate. Investigators can evaluate how 96 different compounds affect the expression pattern for these genes in each plate. This technology will address an unmet need of the agricultural industry - to make efficient use of novel genomics information. This will allow testing of more gene targets including newly identified genes, and will provide information about selectivity and specificity.Proprietary methods allow DNA array technology to be used for the high throughput multiple mRNA assay. Preliminary results demonstrate the feasibility of these methods using mammalian cells. DNA arrays can be applied within each well and retain hybridization specificity. The method is sensitive enough to detect genes expressed at one mRNA molecule per cell from cells grown within one well of a 96-well plate. The researchers propose to apply the approach to cultured plant cells, in order to form a reliable and sensitive screening technology for discovering new compounds that modulate gene expression in crops.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
SBIR Phase II: Gene Signature Screening for Pancreatic Cancer Therapeutics from Sonoran Desert Extracts
  • 批准号:
    1127476
  • 项目类别:
    Standard Grant
  • 资助金额:
    $36.46万
  • 财政年份:
    2011
  • 负责人:
    Richard Kris
  • 依托单位:
SBIR Phase I: Gene signature screening for Pancreatic Cancer Therapeutics from Sonoran Desert extracts
  • 批准号:
    1014372
  • 项目类别:
    Standard Grant
  • 资助金额:
    $0.0万
  • 财政年份:
    2010
  • 负责人:
    Richard Kris
  • 依托单位:
SBIR Phase II: Development and Manufacture of High-Density Plate Washer
  • 批准号:
    0450448
  • 项目类别:
    Standard Grant
  • 资助金额:
    $0.0万
  • 财政年份:
    2005
  • 负责人:
    Richard Kris
  • 依托单位:
SBIR Phase I: Development and Manufacture of High-Density Plate Washer
  • 批准号:
    0319656
  • 项目类别:
    Standard Grant
  • 资助金额:
    $10.0万
  • 财政年份:
    2003
  • 负责人:
    Richard Kris
  • 依托单位:
国内基金
海外基金
Baryogenesis, Dark Matter and Nanohertz Gravitational Waves from a Dark Supercooled Phase Transition
  • 批准号:
    24ZR1429700
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    YUICHIRO NAKAI
  • 依托单位:
ATLAS实验探测器Phase 2升级
  • 批准号:
    11961141014
  • 项目类别:
    国际(地区)合作与交流项目
  • 资助金额:
    3350万元
  • 批准年份:
    2019
  • 负责人:
    刘衍文
  • 依托单位:
地幔含水相Phase E的温度压力稳定区域与晶体结构研究
  • 批准号:
    41802035
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    12.0万元
  • 批准年份:
    2018
  • 负责人:
    张里
  • 依托单位:
基于数字增强干涉的Phase-OTDR高灵敏度定量测量技术研究