FOR 1321: Single-Port Technology for Gastroenterological and Surgical Endoscopic Interventions

在DFG研究小组项目1321的范围内，可以成功实现用于单端口和NOTES手术的机电一体化平台的概念。两种典型干预措施（乙状结肠切除术和内镜下粘膜下剥离术）的实现被定义为初始提案的重要里程碑，这可以在所有单个工作包的积累中完全实现。在此基础上，应审查具体应用的可能性，以便随后继续以前的研究和开发工作。新平台的潜力将用于解决微创和无瘢痕手术的各种核心问题。具体的应用可能性描述如下：1.用于制造患者个体和干预优化器械的适当程序（制造过程的可扩展性（定制器械）2.两个操纵器平台的同时适用性，具有直接合作的可能性（血管内和腹腔内手术）3.用于执行腔内吻合术的平台的改进包括可生物降解的植入物4的开发。将新平台纳入业务工作流程5.这些研究主题对内脏手术中进一步的创伤最小化具有协同作用，在成功实现的情况下，消除了实施外科干预的无瘢痕技术的现有障碍。为了实现工程科学和信息学（医学和微技术，机器人技术等）之间的密切合作。以及临床学科是强制性的。

In the scope of the DFG research group project 1321 a concept of a mechatronic platform for single-port and NOTES surgery could be successfully realized. The realization of two typical interventions (sigmoidal resection and endoscopic submucosal dissection) was defined as an essential milestone for the initial proposal, which could be fully achieved in the accumulation of all single working packages. Based on this, specific application possibilities for the consequent continuation of the previous research and development performance shall be examined. The potential of the new platform will be utilized for the solution of various central questions of minimally invasive and scarless surgery. The specific application possibilities are described as follows: 1. an appropriate procedure for manufacturing of patient individual and intervention optimized instruments (scalability of the manufacturing process (tailored instruments) 2. the simultaneous applicability of two manipulator platforms with the possibility of direct cooperation (intravascular and intraabbominal procedures) 3. the modification of the platform for the execution of endoluminal anastomosis including the development of a biodegradable implant 4. the integration of the new platform into the operative workflow 5. the realization of a theragnostic application possibility These research topics have a synergetic effect on the further trauma minimization in visceral surgery which eliminates, in the case of successful realization, existing barriers for the implementation of scarless techniques of surgical interventions. For the realization a close cooperation between engineering sciences and informatics (medical and microtechnology, robotics etc.) as well as clinical disciplines is mandatory.