MRI: Acquisition of a Multi-Photon Laser Scanning Microscope System

MRI：获取多光子激光扫描显微镜系统

• 批准号: 9977488
• 负责人: Susan Margulies
• 金额: $ 45万
• 依托单位: University of Pennsylvania
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2003-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9977488&HistoricalAwards=false
• 关键词: MRI; Acquisition; Multi; Photon; Laser

Funds are requested for the purchase of a multi-photon microscope to be conveniently located near two of the major Penn Institutes whose faculty will share the equipment. Some 14 users from the School of Engineering and Applied Science, the School of Medicine, and several campus institutes will use the equipment for biomedical and biomaterial research investigations. The new equipment offers significant advantages over existing equipment in imaging penetration depth, sensitivity, photodamage, and the ability to observe multiple fluorophores simultaneously. Specific studies include the effect of environmental stimuli on cells, the microscopic basis of biomaterial behavior, polymer behavior at interfaces, etc. The facility will be made available to researchers at nearby Universities.

需要资金购买一台多光子显微镜，该显微镜位于宾夕法尼亚大学两个主要研究所附近，其教师将共享设备。来自工程与应用科学学院、医学院和几个校园研究所的大约14名用户将使用该设备进行生物医学和生物材料研究调查。与现有设备相比，新设备在成像穿透深度、灵敏度、光损伤以及同时观察多个荧光团的能力方面具有显着优势。具体的研究包括环境刺激对细胞的影响，生物材料行为的微观基础，界面处的聚合物行为等。该设施将提供给附近大学的研究人员。