Xenon as a Probe of Internal Space in Fluids and Porous Media

氙作为流体和多孔介质内部空间的探针

• 批准号: 9979259
• 负责人: Cynthia Jameson
• 金额: $ 55.12万
• 依托单位: University of Illinois at Chicago
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-15 至 2004-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9979259&HistoricalAwards=false
• 关键词: Xenon; Probe; Internal; Space; Fluids

Professor Cynthia Jameson of the University of Illinois at Chicago is supported in the Experimental Physical Chemistry program to perform Nuclear Magnetic Resonance (NMR) studies utilizing Xenon atoms to probe environments difficult to study such as the interior of zeolites, polymers and biomolecules. Her goal is to use these experiments together with ab initio predictions of chemical shift parameters and more standard Monte Carlo statistical models to develop Xenon NMR as an exact quantitative method. Xenon NMR is widely used to study solid samples, but it has not yet been exploited to its full potential. For example, her group will develop the method for accurate determination of competitive adsorption of molecules in zeolite cavities, a key parameter in understanding the catalytic power of zeolites. The effect of counterions in cation-exchanged zeolites will be studied, as well as some kinetics and dynamical studies on these systems. The experiments will provide testing grounds for new theory - improving the potential surfaces between Xenon and coadsorbates (or the zeolite wall) as well as the statistical models for adsorption in zeolites. The experience with zeolites will then be applied to the problem of structure of liquids, polymers, and biological systems. Professor Jameson will conduct mainly theoretical studies analyzing Xenon NMR signals in cyclodextrin, polymers, polymer blends and in globular proteins such as myoglobin, with the goal of understanding the structures of these microheterogeneous chemical environments.Nuclear magnetic resonance (NMR) is a chemical version of the more well-known medical method Magnetic Resonance Imaging (MRI). The use of NMR for understanding basic structural features of solids, liquids, and gases is increasing with the development of new techniques such as Xenon NMR, which has been used to study solid-state structures. The research is timely also due to the recent use of hyperpolarized Xenon for imaging (including clinical applications). In addition to interesting the catalysis community studying zeolites, the work will ultimately be of use in other applications of microporous solids such as separations. Professor Jameson is well known as an outstanding mentor of women and minorities in her laboratories.

伊利诺伊大学芝加哥分校的Cynthia Jameson教授在实验物理化学计划中获得支持，利用氙原子进行核磁共振（NMR）研究，以探测难以研究的环境，如沸石，聚合物和生物分子的内部。 她的目标是将这些实验与化学位移参数的从头计算预测和更标准的蒙特卡罗统计模型一起使用，以开发氙NMR作为精确的定量方法。氙核磁共振被广泛用于研究固体样品，但尚未充分发挥其潜力。例如，她的团队将开发用于精确测定沸石空腔中分子竞争吸附的方法，这是理解沸石催化能力的关键参数。 本文将研究阳离子交换沸石中反离子的作用，以及对这些体系的动力学和动力学研究。 这些实验将为改进氙与共吸附物（或沸石壁）之间的势面以及沸石中吸附的统计模型提供新的理论测试基础。 沸石的经验，然后将适用于液体，聚合物和生物系统的结构问题。 Jameson教授将主要进行理论研究，分析环糊精、聚合物、聚合物共混物和球状蛋白质（如肌红蛋白）中的氙核磁共振信号，以了解这些微异质化学环境的结构。核磁共振（NMR）是更知名的医学方法磁共振成像（MRI）的化学版本。 随着新技术的发展，如用于研究固态结构的氙核磁共振，核磁共振在理解固体、液体和气体的基本结构特征方面的应用越来越多。 这项研究也是及时的，因为最近使用超极化氙成像（包括临床应用）。 除了对研究沸石的催化社区感兴趣之外，这项工作最终将用于微孔固体的其他应用，如分离。 詹姆森教授是众所周知的妇女和少数民族在她的实验室的杰出导师。