Development of a Guided-Inquiry, Collaborative Physical Chemistry Laboratory Course

化学(12)正在开发一门指导探究、协作的物理化学实验室课程。出于对我们的物理化学实验室应该反映现代实验室进行测量的方式的关注，以及普通化学的成功改革的启发，我们正在物理化学实验室课程中采用和实施被接受的以问题为基础的教学策略，即引导探究和协作学习。我们的主要目标是：1)开发两个指导性探究、协作项目，学生在其中学习制定实验室程序、收集样本和获取数据、分析和解释数据，并有效地交流他们的结果；2)为我们的物理化学实验室配备仪器，使我们能够开发一个指导性探究、协作项目，该项目以制药行业面临的问题为中心，药物物质的多形性。实验室项目本身的方法将改编自药学研究文献和化学教育文献中发表的实验。新的仪器包括差示扫描量热仪和带热阶段的偏光显微镜这些项目正在开发、实施、评估和修改，为期两年。物理化学实验室教学方式的改变对整个化学课程产生了重大影响。采用和实施指导性探究教学方法开始了化学实验课程的改革，因为我们的实验室课程以前都没有使用过这种方法。两个指导式探究式协作物理化学实验室项目的开发和实施正在推动整个化学课程中实验室课程的变化，将以问题为基础的方法注入我们的实验室课程，并提供可以整合到我们课程中的工具。

Chemistry (12) A guided-inquiry, collaborative physical chemistry laboratory course is being developed. Motivated by a concern that our physical chemistry laboratories should reflect the way measurements are carried out in modern laboratories, and inspired by the successful reforms of general chemistry, we are adapting and implementing the accepted pedagogical strategies of guided-inquiry and collaborative learning in a problem based approach in a physical chemistry laboratory course. Pedagogical strategies used in the New Traditions systemic chemistry initiative, and more generally discussed by the NSF report on Curricular Developments in the Analytical Sciences, are being adapted.Our primary goals are: 1) to develop two guided-inquiry, collaborative projects where the students learn to develop laboratory procedures, gather samples and obtain data, analyze and interpret data, and effectively communicate their results and 2) to equip our physical chemistry laboratory with instruments which allow us to develop a guided-inquiry, collaborative project which centers on a problem facing the pharmaceutical industry, polymorphism of drug substances. The methodology of the laboratory projects themselves will be adapted from the pharmaceutical research literature and from experiments published in the chemical education literature. New instruments include a differential scanning calorimeter and a polarized light microscope with a hot stage The projects are being developed, implemented, evaluated, and revised during a two-year time frame.Changing the way the physical chemistry laboratory is taught is having a significant impact on the entire chemistry curriculum. Adapting and implementing a guided-inquiry approach begins a reform of the chemistry laboratory curriculum because none of our laboratory courses previously used that approach. The development and implementation of two guided-inquiry collaborative physical chemistry laboratory projects is promoting changes in the laboratory courses across the chemistry curriculum, injecting a problem based approach into our laboratory curriculum, and providing instruments which can be integrated into our courses.