Use of an NMR Spectrometer to Improve the Chemistry Curriculum

化学（12）使用现代核磁共振（NMR）谱仪和改编其他机构开发并发表在各种化学期刊上的相关实验，使化学课程能够按计划持续改进。该机构的本科教育愿景是开发一套实验室经验，经过深思熟虑的排序和整合，以促进学生在所有课程中的全面智力和技能发展。核磁共振波谱学自诞生以来一直是化学家最强大的结构工具之一。在过去的二十年里，磁场强度和稳定性、计算机硬件、软件和用户界面方面的巨大进步，使得更复杂的实验成为可能。今天，分子相互作用、动力学和复杂结构表征的详细研究正在成为常规。如果毕业生要解决生物化学、地球化学、材料科学和环境化学领域的复杂问题，如何获取分子水平信息的知识是极其重要的。在许多本科化学课程中，本科教育与研究生或工业研究之间最大的技术差距往往是核磁共振波谱学。在课程中使用现代核磁共振波谱仪使本科生能够迎接工业界和学术界提出的研究挑战。该光谱仪为学生提供变温度、高分辨率、质子和碳-13核磁共振光谱以及自旋晶格弛豫数据、生化动力学中的磁化转移光谱、极化转移（DEPT）光谱以及各种二维光谱，如COSY、NOESY、ROESY、TOSY、HMQC。固态核磁共振功能也允许获得魔角旋转交叉极化（CPMAS）核磁共振光谱。

Chemistry (12)Use of a modern nuclear magnetic resonance (NMR) spectrometer and adaptation of relevant experiments developed at other institutions and published in a variety of chemistry journals enable continued planned improvements in the chemistry curriculum. The institution's vision for undergraduate education is to develop a set of laboratory experiences that are thoughtfully sequenced and integrated to promote the full intellectual and skills development of students in all courses. Nuclear magnetic resonance spectroscopy has been one of the most powerful structural tools available to chemists since its inception. Within the last two decades, tremendous improvements in field strength and stability, computer hardware, software, and user interfaces, have allowed much more complex experiments. Today, detailed studies of molecular interactions, dynamics, and the characterization of complex structures are becoming routine. Knowledge of how to access molecular level information is extremely important if graduates are to tackle complex questions in the areas of biochemistry, geochemistry, materials science, and environmental chemistry. In many undergraduate chemistry programs, the greatest technology gap between undergraduate education and graduate or industrial research is often in NMR spectroscopy. Use of a modern NMR spectrometer in the curriculum prepares undergraduates to meet research challenges presented in industry and academia. This spectrometer provides students with variable temperature, high resolution, proton and carbon-13 NMR spectra as well as spin-lattice relaxation data, magnetization transfer spectra in biochemical kinetics, polarization transfer (DEPT) spectra, and a variety of 2-D spectra such as COSY, NOESY, ROESY, TOSY, HMQC. Solid-state NMR capabilities also allow obtaining magic angle spinning cross polarization (CPMAS) NMR spectra.