SGER: Comparative Studies of Senescence in Natural Populations of Guppies

SGER：孔雀鱼自然种群衰老的比较研究

• 批准号: 9986801
• 负责人: David Reznick
• 金额: $ 2.72万
• 依托单位: University of California-Riverside
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-01-01 至 2001-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9986801&HistoricalAwards=false
• 关键词: SGER; Comparative; Studies; Senescence; Natural

9986801 ReznickThis is a comparative study of aging in natural populations of guppies based on individually mark as many as 2,000 guppies each from two populations. One population is from an environment where they naturally experience low mortality rates, so that they have high life expectancies. The other population was recently introduced from a high mortality rate environment to a low mortality rate environment, where differences in mortality rate are caused by differences in the predators that guppies co-occur with. This second population has already evolved to some extent in response to the lower mortality rates in the new environment. A recently developed statistical test will determine if there is an acceleration in mortality rates in the oldest age classes of guppies and hence if there are differences among these two populations in the rate of acceleration of mortality rate, i.e., senescence. Theory predicts that there should be differences in the rate of senescence in these two populations. The broader goal is to determine why animals age from an evolutionary perspective. While hundreds of investigators are studying aging, very few are considering why we see differences among populations or species in the rate of aging, even though a theory predicting why such differences evolve was proposed over 40 years ago. This study tests these predictions.

9986801 Reznick这是一项孔雀鱼自然种群衰老的比较研究，基于对来自两个种群的2,000只孔雀鱼进行单独标记。 一个群体来自一个自然死亡率低的环境，因此他们的预期寿命很高。 另一个种群是最近从高死亡率环境引入到低死亡率环境的，其中死亡率的差异是由孔雀鱼共同出现的捕食者的差异引起的。 这第二个种群已经在一定程度上进化，以应对新环境中较低的死亡率。 最近开发的统计测试将确定孔雀鱼最老年龄组的死亡率是否加速，因此这两个种群之间的死亡率加速率是否存在差异，即，衰老 理论预测，这两个群体的衰老速度应该存在差异。更广泛的目标是从进化的角度确定动物衰老的原因。 虽然数百名研究人员正在研究衰老，但很少有人考虑为什么我们会看到种群或物种之间衰老速度的差异，尽管40多年前就提出了预测这种差异进化原因的理论。 这项研究验证了这些预测。