FASEB Conference on Nucleic Acid Enzymes: Structures, Mechanisms and Novel Applications; June 18-22, 2000, Saxtons River, Vermont

FASEB 核酸酶会议:结构、机制和新应用;

基本信息

项目摘要

This conference will focus on the structures, mechanisms, biological roles, and practical applications of enzymes that act on DNA and RNA. The meeting aims to attract a broad cross-disciplinary group of scientists with expertise in structural biology, biochemistry, and cell biology. This meeting will be the fourth sponsored by the Federation of American Societies of Experimental Biology (FASEB) in the areas of nucleic acid enzymology; the most recent in this series was held in 1998, with support from the National Science Foundation. The explosive pace of discovery of new enzymes that act on nucleic acids, the wealth of mechanistic information emerging from high resolution structural analysis, and the central role of DNA and RNA enzymology in biotechnology are factors that make this next FASEB 2000 meeting extremely timely and topical. The scientific program will consist of nine sessions of oral presentations by distinguished invited speakers. The subjects of the sessions include the following areas: (1) DNA repair enzymes; (2) DNA and RNA polymerases; (3) Transposition and recombination; (4) DNA and RNA modification enzymes; (5) Helicases and nucleic acid-dependent NTPases; (6) RNA and DNA catalysts; (7) Cleavage and degradative enzymes; and (8) New applications for nucleic acid enzymes and new insights from genomics into the evolution of enzyme systems. The organizers have recruited leading investigators to serve as discussion leaders for these sessions. The program will also include daily poster sessions. The conference aims to highlight the parallels and differences between enzymes involved in DNA metabolism and those of the RNA world. Hence, the program has been configured so that most sessions will include talks on both RNA and DNA transactions. The intimate format of the conference is designed to promote free exchange of information and ideas among researchers who work on RNA and DNA enzymes - thereby expediting research in both fields. Such research enhances our understanding of the natural world and thus our ability to use it for the greater benefit of society. All attendees will be asked to present posters on their research. To encourage career development of junior scientists, six outstanding posters from the ranks of graduate students and post-doc attendees will be selected for oral presentations. Financial support from NSF will be targeted specifically to the six junior scientists and will also be used to defray expenses for the sessions listed above.
本次会议将重点讨论作用于DNA和RNA的酶的结构,机制,生物学作用和实际应用。会议旨在吸引具有结构生物学,生物化学和细胞生物学专业知识的广泛的跨学科科学家小组。这次会议将是美国实验生物学学会联合会(FASEB)在核酸酶学领域主办的第四次会议;最近一次是在1998年举行的,得到了国家科学基金会的支持。 新的酶的发现,作用于核酸,从高分辨率结构分析中出现的机械信息的财富,以及DNA和RNA酶学在生物技术中的中心作用的爆炸性步伐是使这个下一个FASEB 2000会议非常及时和专题的因素。 科学计划将包括九场由杰出的特邀演讲者进行的口头报告。 会议的主题包括以下领域:(1)DNA修复酶;(2)DNA和RNA聚合酶;(3)转座和重组;(4)DNA和RNA修饰酶;(5)解旋酶和依赖核酸的NTPases;(6)RNA和DNA催化剂;(7)切割和降解酶;(8)核酸酶的新应用和从基因组学到酶系统进化的新见解。组织者招募了主要的调查人员担任这些会议的讨论领导人。该计划还将包括每日海报会议。 该会议旨在强调参与DNA代谢的酶与RNA世界的酶之间的相似性和差异。因此,该计划已被配置,以便大多数会议将包括RNA和DNA交易的会谈。会议的亲密形式旨在促进从事RNA和DNA酶研究的研究人员之间的信息和想法的自由交流-从而加快这两个领域的研究。 这种研究提高了我们对自然世界的理解,从而提高了我们利用自然世界为社会造福的能力。 所有与会者将被要求提交他们的研究海报。为了鼓励年轻科学家的职业发展,将从研究生和博士后与会者中选出六名优秀的海报进行口头陈述。NSF的财政支持将专门针对六名年轻科学家,并将用于支付上述会议的费用。

项目成果

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Stewart Shuman其他文献

Structure-Function Analysis of the mRNA Cap Methyltransferase of <em>Saccharomyces cerevisiae</em>
  • DOI:
    10.1074/jbc.272.23.14683
  • 发表时间:
    1997-06-06
  • 期刊:
  • 影响因子:
  • 作者:
    Shuang Ping Wang;Stewart Shuman
  • 通讯作者:
    Stewart Shuman
Structure and emin vivo/em psoralen DNA crosslink repair activity of mycobacterial Nei2
结核分枝杆菌 Nei2 的结构及体内/体外补骨脂素 DNA 交联修复活性
  • DOI:
    10.1128/mbio.01248-24
  • 发表时间:
    2024-07-26
  • 期刊:
  • 影响因子:
    4.700
  • 作者:
    Garrett M. Warren;Stewart Shuman
  • 通讯作者:
    Stewart Shuman
Genetic suppressor screen identifies Tgp1 (glycerophosphocholine transporter), Kcs1 (IPsub6/sub kinase), and Plc1 (phospholipase C) as determinants of inositol pyrophosphate toxicosis in fission yeast
基因抑制筛选确定 Tgp1(甘油磷胆碱转运蛋白)、Kcs1(IP6 激酶)和 Plc1(磷脂酶 C)为裂殖酵母中焦磷酸肌醇中毒的决定因素
  • DOI:
    10.1128/mbio.03062-23
  • 发表时间:
    2024-01-23
  • 期刊:
  • 影响因子:
    4.700
  • 作者:
    Lauren Bednor;Ana M. Sanchez;Angad Garg;Stewart Shuman;Beate Schwer
  • 通讯作者:
    Beate Schwer
Structure-guided Mutational Analysis of the Nucleotidyltransferase Domain of <em>Escherichia coli</em> NAD<sup>+</sup>-dependent DNA Ligase (LigA)
  • DOI:
    10.1074/jbc.m413685200
  • 发表时间:
    2005-04-01
  • 期刊:
  • 影响因子:
  • 作者:
    Hui Zhu;Stewart Shuman
  • 通讯作者:
    Stewart Shuman
Fission yeast metabolome dynamics during phosphate starvation and replenishment
磷饥饿和补充期间裂殖酵母代谢组动态
  • DOI:
    10.1128/mbio.00241-25
  • 发表时间:
    2025-02-25
  • 期刊:
  • 影响因子:
    4.700
  • 作者:
    Ana M. Sanchez;Aye K. Kyaw;Sara Nunes Violante;Angad Garg;Justin R. Cross;Stewart Shuman
  • 通讯作者:
    Stewart Shuman

Stewart Shuman的其他文献

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