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中文摘要
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描述(由申请者提供):2008年戈登核酸研究会议将于2008年6月1日至6日在罗德岛州纽波特的萨尔维里贾纳大学举行,现申请部分资助。核酸戈登研究会议是首次报道有关核酸结构和功能的重要发现的关键场所。传统上,戈登会议吸引了来自生物物理化学、结构生物学、细胞生物学和遗传学等不同领域的科学家,促进了跨学科的交流,这在更专门的会议中是罕见的。会议讨论了DNA和RNA在正常生长和发育以及癌症、遗传性疾病以及病毒和微生物感染的病理状态中的基本作用。2008年会议上的正式研究报告将强调基本的生物学过程,包括表观遗传学、DNA复制、细胞对DNA损伤的反应、RNA转录、加工和运输、核糖体组装,以及生物信息学的新兴领域,以及RNA对基因表达的调控。除了代表这些领域研究的前沿外,还将选择发言者和会议主席,以反映年龄、性别和国籍的平衡。会议还将促进资深科学家、青年研究人员和考虑从事核酸研究工作的学生之间的非正式互动,此外还将突出正式研究报告的日程安排。例如,在正式讲座之后,分配了相当多的时间进行讨论。海报会议和可选的娱乐活动将进一步刺激非正式互动。与会者是根据他们的科学成就和在核酸研究方面的职业潜力被招募参加2008年会议的。代表不足的少数族裔将被特别鼓励参加。将特别努力强调初级教员、博士后研究人员和学生的研究成就,以及现有的研究人员。
英文摘要
DESCRIPTION (provided by applicant): Partial support is requested for the 2008 Gordon Research Conference on Nucleic Acids, to be held June 1-6, 2008, at Salve Regina University, Newport, Rhode Island. The Nucleic Acids Gordon Research Conference serves as a key venue for the first reports of important discoveries on the structure and function of nucleic acids. Traditionally attracting scientists from fields as diverse as biophysical chemistry, structural biology, cell biology and genetics, this Gordon Conference facilitates cross-disciplinary exchanges that are rare in more specialized meetings. The meeting addresses the fundamental roles of DNA and RNA in normal growth and development and in the pathological states that underlie cancer, hereditary disease and viral and microbial infections. Formal research presentations at the 2008 Conference will emphasize basic biological processes including epigenetics, DNA replication, cellular responses to DNA damage, RNA transcription, processing and transport, and ribosome assembly, as well as emerging areas of bioinformatics, and the regulation of gene expression by RNAs. In addition to representing the leading edge of research in these areas, speakers and session chairs will be chosen to reflect a balance in age, gender, and nationality. The Conference will also promote informal interactions among established senior scientists, young investigators and students considering careers in nucleic acids research, in addition to featuring an outstanding schedule of formal research presentations. For example, considerable time is allotted for discussion following formal lectures. Poster sessions and optional recreational activities will further stimulate informal interactions. Participants are being recruited to the 2008 Conference based on their scientific accomplishments and their potential for careers in nucleic acids research. Underrepresented minorities will be especially encouraged to attend. Special efforts will be made to emphasize research accomplishments of junior faculty, postdoctoral researchers and students in addition to established investigators.
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Mismatch Repair Interactions
Mismatch Repair Interactions
CORE--FERMENTATION FACILITY
  • 批准号:
    6268738
  • 项目类别:
  • 资助金额:
    $17.35万
  • 财政年份:
    1998
  • 负责人:
    PAUL LAWRENCE MODRICH
  • 依托单位:
CORE--FERMENTATION FACILITY
  • 批准号:
    6236138
  • 项目类别:
  • 资助金额:
    $16.83万
  • 财政年份:
    1997
  • 负责人:
    PAUL LAWRENCE MODRICH
  • 依托单位:
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: