Ultratrace Chemical Analysis with Nanotubule Membranes - Fundamental Studies

使用纳米管膜进行超痕量化学分析 - 基础研究

• 批准号: 9987646
• 负责人: Charles Martin
• 金额: $ 32.7万
• 依托单位: University of Florida
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-06-01 至 2006-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9987646&HistoricalAwards=false
• 关键词: Ultratrace; Chemical; Analysis; Nanotubule; Membranes

This project, which is supported in the Analytical and Surface Chemistry program conducts fundamental studies on the effects of analyte molecules on current flow through membranes. Conducted by Dr. Charles Martin and his group at the University of Florida, the research uses a membrane containing gold nanotubes to detect analyte concentrations by measuring enhanced resistance as an analyte molecule passes through the membrane. The tubes are of molecular dimensions ( 1 nm) and extraordinarily low detection limits are possible. The project addresses four main areas; 1) the mechanism by which the analyte is transferred from the bulk solution to the mouths of the nanotubes, 2) the nature of the partitioning of the analyte into the nanotubes, 3) the role of hindered diffusion of the analyte within the nanotubes on the response mechanism, and 4) the fundamental detection limits achievable by this device. This research develops basic information on how membranes containing gold nanotubes can be used to analyze extremely low levels of organic species. Information from this research will be useful to determine the size and number of extremely small (eg virus) particles.

该项目得到了分析和表面化学项目的支持，对分析物分子对通过膜的电流的影响进行了基础研究。 由佛罗里达大学的查尔斯·马丁博士和他的小组进行的这项研究使用了一种含有金纳米管的膜，通过测量分析物分子穿过膜时增强的电阻来检测分析物浓度。 管的分子尺寸（1 nm）和非常低的检测限是可能的。 该项目涉及四个主要领域; 1）分析物从本体溶液转移到纳米管嘴的机制，2）分析物分配到纳米管中的性质，3）纳米管内分析物受阻扩散对响应机制的作用，以及4）该设备可实现的基本检测限。这项研究开发了关于如何使用含有金纳米管的膜来分析极低水平的有机物质的基本信息。 这项研究的信息将有助于确定极小（如病毒）颗粒的大小和数量。